Suberoylanilide hydroxamic acid, a potent histone deacetylase inhibitor; its X-ray crystal structure and solid state and solution studies of its Zn(II), Ni(II), Cu(II) and Fe(III) complexes

Griffith, Darren M.; Szőcs, Béla; Keogh, Tomás; Suponitsky, Kyrill Yu.; Farkas, Etelka; Buglyó, Péter; Marmion, Celine J.

doi:10.1016/j.jinorgbio.2011.03.003

Cited by 75 publications

(37 citation statements)

References 34 publications

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“…As well-known chelating collector, hydroxamic acids are effective ligands with metal ions. The chelating performance of hydroxamic acids with transition metals including Fe, Ni, Cu and Zn has been studied through theoretical and experimental methods [4][5][6]. Research of chelation between hydroxamic acids and Pb has also been reported [7].…”

Section: Introductionmentioning

confidence: 99%

Study on the Activation of Scheelite and Wolframite by Lead Nitrate

2015

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Abstract:The activation of scheelite and wolframite by lead nitrate with benzohydroxamic acid (BHA) as collector was investigated by means of micro flotation test, zeta potential measurement, X-ray photoelectron spectroscopy (XPS) analyses and density functional theory (DFT) calculation. The flotation results confirmed that the addition of lead nitrate can markedly enhance the recovery of scheelite and wolframite. In the zeta potential curves obvious positive shifts were observed with the presence of lead nitrate. Lead was detected on mineral surface in microscopic analysis and the survey XP spectra. Both the electrokinetic study and XPS analyses indicated that lead ion can be adsorbed onto mineral surface. In DFT calculation, the coordination model of BHA with metal hydroxyl ions (Ca (

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Section: Introductionmentioning

confidence: 99%

Study on the Activation of Scheelite and Wolframite by Lead Nitrate

2015

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“…However, hydroxamic acids possess stronger abilities for selectively chelating metal ions [1][2][3][4][5][6][7]. Commonly, the two O atoms in carbonyl and hydroxyl groups of a hydroxamate molecule bond with metal cation to form a five-membered ring structure.…”

Section: Introductionmentioning

confidence: 99%

A novel collector 2-ethyl-2-hexenoic hydroxamic acid: Flotation performance and adsorption mechanism to ilmenite

Zhong

Tang

et al. 2015

Applied Surface Science

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“…5 It is well established that metal-chelating motifs bind tightly to the Zn(II) ion in the active site of HDAC enzymes and can lead to reversible inhibition of their biological function. 6 HDAC inhibitors (HDACi) have great potential as therapeutic agents, with several advancing into clinical trials; and multiple panactive HDACi are FDA approved for T-cell lymphoma and multiple myeloma.…”

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confidence: 99%