Subglottic haemangioma in infancy

The Biology and Management of Subglottic Hemangioma: Past, Present, Future

“…They reported an average regression time of 9 months with the age range at decannulation of 1 to 2 years in 17 patients. Other studies have also reported success with the application of radioactive gold implant 18,19 . However, because of concerns for associated risk of damage to the normal airway mucosa and secondary malignancy, this treatment modality was abandoned in the late 1970s.…”

Subglottic haemangioma in children

“…Prior to this, the mortality rate had been 50 per cent (Ferguson and Flake, 1961). Radioactive gold grain implantation had also been tried (Bruce, 1978;Jokinen et al, 1981;Holborow and Mott, 1973). However, owing to the potential hazards of radiotherapy in children (Fost and Esterly.…”

“…A great many therapeutic measures have been advocated for the treatment of subglottic haemangioma including: low dose radiotherapy (Ferguson and Flake, 1961;Tefft, 1966), radioactive gold grain implantation (Holborow and Mott, 1973;Bruce, 1978), radium (Nordbert and Sundberg, 1963), corticosteroids (Cohen, 1969), sclerosing fluids (Garfinkle and Hand|er, 1980;Pierce, 1962), cryosurgery (Jokinen et al, 1981Charachon et al, 1977), submucosal excision by laryngofissure (Calcaterra, 1968;Mawson, 1961;Zakrewski et al, 1963), and most recently the carbon dioxide LASER (Healey etal., 1980).…”