Subglottic laryngitis – Changes in therapy approach over the past 20 years

Penezić, Ana; Ivkić, Mirko; Ivkić, Boris; Baudoin, Tomislav

doi:10.1016/j.anl.2015.03.004

Cited by 7 publications

(2 citation statements)

References 27 publications

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“…Parainfluenza virus type 1 is the most common cause of pseudocroup, especially during the fall and winter epidemics when it reaches the major incidence peak [1]. Although pseudocroup is usually a mild self-limited disease, it might be a potentially life-threatening condition demanding hospitalization and prompt management and airway preservation [2–5].…”

Section: Introductionmentioning

confidence: 99%

The Acute Phase Proteins Reaction in Children Suffering from Pseudocroup

Pucher

Sobieska

Grzegorowski

et al. 2019

Mediators of Inflammation

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The aim of the study was to evaluate the inflammatory reaction in children with pseudocroup and compare it with other laryngological diseases according to the available literature data. The study group included 51 children hospitalized because of pseudocroup. The measurements of the acute phase proteins (APP), such as C-reactive protein (CRP), alpha-1-antitrypsin (AT), alpha-1-antichymotrypsin (ACT), alpha-1-acid glycoprotein (AGP), ceruloplasmin (Cp), transferrin (Tf), alpha-2-macroglobulin (A2M), and haptoglobin (Hp) were obtained at 3 time points. The glycosylation profiles of AGP, ACT, and Tf were completed. An increased AGP level was observed in girls. The AGP glycosylation revealed the advantage of the W0 variant over the W1 variant. W1 and W2 were decreased in boys. W3 emerged in boys. The Tf concentration and T4 variant were lower compared to the control group. The A2M level was lower after treatment. The Hp and AT levels were decreased a few weeks later. The ACT glycosylation revealed a decrease of the A4 variant in boys. In conclusion, the inflammatory reaction during pseudocroup was of low intensity. The APP glycosylation suggested a chronic process. In a follow-up investigation, no normalization of the parameters was noted, but signs of persistent inflammation were observed.

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Section: Introductionmentioning

confidence: 99%

The Acute Phase Proteins Reaction in Children Suffering from Pseudocroup

Pucher

Sobieska

Grzegorowski

et al. 2019

Mediators of Inflammation

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“…В последующем у этих детей практически не отмечалось формирование бронхиальной астмы. Полученные результаты согласуются с данными литературы о том, что в основе рецидивирования СЛТ лежат процессы аллергического воспаления и наследственной или приобретенной гиперреактивности дыхательных путей [11].…”

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The problems associated with the treatment of stenosing laryngotracheitis in the children (the results of the 35 year-long experience)

Сафроненко

Davydova

Karpov

et al. 2017

Vestn. otorinolaringol.

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Stenosing laryngotracheitis (SLT) affecting the children is considered to be an emergency pediatric condition associated with ENT pathology. Its treatment presents a serious challenge for otolaryngologists, pediatricians, specialists in communicable diseases, allergologists, etc. We have undertaken a retrospective analysis of the available data with a view to summarizing the tendencies in the evolution of SLT morbidity. The results of the 35 year-long experience with the use of the currently available therapeutic strategies for the treatment of the children suffering from stenosing laryngotracheitis are presented. Special emphasis is laid on the advantages of the combined treatment of the patients presenting with this condition based at a specialized infectious department with the participation of an otorhinolaryngologist.

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