Subject-Specific Computational Fluid-Structure Interaction Modeling of Rabbit Vocal Fold Vibration

Avhad, Amit; Li, Zheng; Wilson, Azure; Sayce, Lea; Chang, Siyuan; Rousseau, Bernard; Luo, H. L.

doi:10.3390/fluids7030097

Cited by 4 publications

(1 citation statement)

References 46 publications

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“…During recent years, simulations have advanced considerably (Bodaghi et al, 2021;Tokuda and Shimamura, 2017;Yoshinaga et al, 2017) towards a state where full-scale aeroacoustic simulations on realistic CT-or MRI-based geometries are possible. It can be anticipated that these simulations could be used for subject-specific pre-surgical predictions of vocal fold oscillations (Avhad et al, 2022). These phonation simulations are useful and help to improve the voice quality for subjects suffering from various vocal fold dysfunctions (Falk et al, 2021;Sadeghi et al, 2019a,b), or evaluate potential effects on voice production affected by an implant insertion in medialization laryngoplasty (Zhang et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Anisotropic Minimum Dissipation Subgrid-Scale Model in Hybrid Aeroacoustic simulations of Human Phonation

Lasota¹,

Šidlof²,

Maurerlehner³

et al. 2023

Preprint

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This article deals with large-eddy simulations of 3D incompressible laryngeal flow followed by acoustic simulations of human phonation of five cardinal english vowels /u, i, A, o, ae/. The flow and aeroacoustic simulations were performed in OpenFOAM and in-house code openCFS, respectively. Given the large variety of scales in the flow and acoustics, the simulation is separated into two steps: (1) computing the flow in the larynx using the finite volume method on a fine 2.2M grid followed by (2) computing the sound sources separately and wave propagation to the radiation zone around the mouth using the finite element method on a coarse 33k acoustic grid. The numerical results showed that the anisotropic minimum dissipation model, which is not well known since it is not available in common CFD software, predicted stronger sound pressure levels at higher harmonics and especially at first two formants than the wall-adapting local eddy-viscosity model. We implemented the model as a new open library in OpenFOAM and deployed the model on turbulent flow in the larynx with positive impact on the quality of simulated vowels. Numerical simulations are in very good agreement with positions of formants from measurements.[https://doi.org(DOI number)][XYZ] Pages: 1-15

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Section: Introductionmentioning

confidence: 99%

Anisotropic Minimum Dissipation Subgrid-Scale Model in Hybrid Aeroacoustic simulations of Human Phonation

Lasota¹,

Šidlof²,

Maurerlehner³

et al. 2023

Preprint

View full text Add to dashboard Cite

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Computational fluid–structure interaction in biology and soft robots: A review

Pramanik,

Verstappen,

Onck

2024

Physics of Fluids

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The omnipresence of fluid–structure interaction (FSI) in biological systems is indisputable—from the vibration of leaves to the locomotion of fish, to the flying of birds, and to the cardiovascular biomechanics; FSI is indeed ubiquitous. Even in stimuli-responsive soft robots that typically operate inside a fluid medium, these physical interactions are prevalent. Therefore, it becomes mandatory to have a thorough understanding of their fully coupled physics involving strong two-way interaction between the solid and fluid domains. Although state-of-the-art computational frameworks and robust numerical techniques have been developed to study their complex physical mechanisms and associated nonlinearities involving multiple spatiotemporal scales, we believe that a timely review of the current development, emerging techniques, and future challenges in computational FSI would further stimulate research along this direction. Therefore, we explore the broad landscape of the myriad research avenues that herald FSI emphasizing their manifold occurrences in biology and advanced soft robotic technologies, while underlining the plethora of numerical techniques adopted to study these fundamental phenomena.

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An Integrated Experimental-Computational Study of Vocal Fold Vibration in Type I Thyroplasty

Avhad,

Wilson,

Sayce

et al. 2024

Journal of Biomechanical Engineering

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Subject-specific computational modeling of vocal fold vibration was integrated with an ex vivo animal experiment of type 1 thyroplasty to study the effect of the implant on the vocal fold vibration. In the experiment, a rabbit larynx was used to simulate type 1 thyroplasty, where one side of the vocal fold was medialized with a trans-muscular suture while the other side was medialized with a silastic implant. Vocal fold vibration was then achieved by flowing air through the larynx and was filmed with a high-speed camera. The 3D computational model was built upon the pre-operative scan of the laryngeal anatomy. This subject-specific model was used to simulate the vocal fold medialization and then the fluid-structure interaction of the vocal fold. Model validation was done by comparing the vocal fold displacement with post-operative scan (for medialization), and by comparing the vibratory characteristics with the high-speed images (for vibration). These comparisons showed the computational model successfully captured the effect of the implant and thus has the potential for pre-surgical planning.

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Subject-Specific Computational Fluid-Structure Interaction Modeling of Rabbit Vocal Fold Vibration

Cited by 4 publications

References 46 publications

Anisotropic Minimum Dissipation Subgrid-Scale Model in Hybrid Aeroacoustic simulations of Human Phonation

Anisotropic Minimum Dissipation Subgrid-Scale Model in Hybrid Aeroacoustic simulations of Human Phonation

Computational fluid–structure interaction in biology and soft robots: A review

An Integrated Experimental-Computational Study of Vocal Fold Vibration in Type I Thyroplasty

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