2023
DOI: 10.1016/j.jad.2023.04.138
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Subjective and objective sleep and circadian parameters as predictors of depression-related outcomes: A machine learning approach in UK Biobank

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Cited by 13 publications
(5 citation statements)
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“…Of the 20 selected studies, eight ( 51 58 ) investigated suicide-related outcomes in the general population [including two studies in youth ( 51 , 52 ) and two in elderly ( 57 , 58 )]. Six studies ( 59 64 ) focused on individuals with a diagnosis of major depressive disorder (MDD) or mood-related disorders [two recruited from psychiatric hospitals ( 61 , 63 ), one of antidepressant users recruited from either the Australian Genetics of Depression Study or through the nationwide Pharmaceutical Benefits Scheme database ( 62 )], two from the general population (i.e., UK Biobank participants that voluntarily enrolled in the study, and participants of the Brazilian Longitudinal Study of Adult Health, consisting of public institutions’ employees) that met criteria for common mental disorders ( 59 , 60 ), one from retrospective analysis of health record data ( 64 ), and one ( 65 ) focused on individuals diagnosed with multiple sclerosis. Five studies ( 66 70 ) investigated individuals who were in contact with mental health services [two for emergency department visits ( 66 , 68 ), and the remaining for substance-related services ( 67 ), general help-seeking ( 69 ), and admission to mental health wards ( 70 )].…”
Section: Resultsmentioning
confidence: 99%
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“…Of the 20 selected studies, eight ( 51 58 ) investigated suicide-related outcomes in the general population [including two studies in youth ( 51 , 52 ) and two in elderly ( 57 , 58 )]. Six studies ( 59 64 ) focused on individuals with a diagnosis of major depressive disorder (MDD) or mood-related disorders [two recruited from psychiatric hospitals ( 61 , 63 ), one of antidepressant users recruited from either the Australian Genetics of Depression Study or through the nationwide Pharmaceutical Benefits Scheme database ( 62 )], two from the general population (i.e., UK Biobank participants that voluntarily enrolled in the study, and participants of the Brazilian Longitudinal Study of Adult Health, consisting of public institutions’ employees) that met criteria for common mental disorders ( 59 , 60 ), one from retrospective analysis of health record data ( 64 ), and one ( 65 ) focused on individuals diagnosed with multiple sclerosis. Five studies ( 66 70 ) investigated individuals who were in contact with mental health services [two for emergency department visits ( 66 , 68 ), and the remaining for substance-related services ( 67 ), general help-seeking ( 69 ), and admission to mental health wards ( 70 )].…”
Section: Resultsmentioning
confidence: 99%
“…Lyall et al ( 59 ) assessed n = 19,389 individuals from the UK Biobank ( 72 ) that met criteria for broad major depression, defined via the following: analysis of the baseline and follow-up mental health questionnaires, ICD-10 codes for mood disorders (F32-F34, F38, F39), and nurse-led interviews. This population was then further subdivided based on indication of suicidal thoughts and behaviors present on the included questionnaires.…”
Section: Resultsmentioning
confidence: 99%
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“…On one hand, trauma can disrupt the balance of the gut microbiota, potentially leading to the development of neuropsychiatric sequelae, which is consistent with published literature ( 6 , 8 ).On the other hand, there is an increase in certain beneficial bacteria, which helps the host adapt to these changes. For instance, higher levels of Verrucomicrobia and Lentisphaerae are associated with better sleep quality ( 47 ),which is known to influence the onset and severity of depression ( 48 ).Several studies have shown that a sustainable abundance of Akkermansia and Butyricimonas can alleviate depressive symptoms ( 46 , 49 ).Bacillus licheniformis and Lactobacillales, recognized as probiotics, have been applied in pre-clinical trials to moderate anxiety and depression ( 50 , 51 ).These bacteria can alleviate stress and reduce symptoms of MDD in the host by producing or influencing certain metabolites, such as SCFAs. SCFAs are recognized for their broad range of health benefits in mammals, including anti-inflammatory activity and potential neuroprotection ( 41 ).Such SCFAs can cross the blood-brain barrier and modulate neuroinflammation, neurotransmission, and brain cell integrity ( 52 , 53 ).…”
Section: Discussionmentioning
confidence: 99%