Subjective sleep quality in cystic fibrosis

Milross, Maree; Piper, Amanda J.; Norman, Mark; Dobbin, Catherine J.; Grunstein, Ronald R.; Sullivan, Colin E.; Bye, Peter

doi:10.1016/s1389-9457(01)00157-5

Cited by 66 publications

(55 citation statements)

References 22 publications

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“…In addition, our study demonstrated that the degree of sleep disruption in children and adolescents with CF was correlated with severity of lung disease. This finding confirms previous studies in adult CF showing the association between subjective sleep quality and severity of lung disease [15,16].…”

Section: Discussionsupporting

confidence: 92%

“…Only one study reported no difference in sleep architecture between adult CF and controls [14]. These changes in sleep architecture were associated with subjective sleep complaints [15]. In the current study, we showed that children and adolescents with CF had a significant decrease in SE and REM sleep consistent with previous findings from adult population.…”

Section: Discussionsupporting

confidence: 90%

“…Secondly, our control subjects were children and adolescents who underwent a sleep study in our sleep laboratory and were found to have normal study. [5,[14][15][16]. All of these studies focused only on adult population.…”

Section: Discussionmentioning

confidence: 99%

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Sleep architecture in children and adolescents with cystic fibrosis and the association with severity of lung disease

et al. 2007

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Previous studies have shown that sleep complaints are common in adult patients with cystic fibrosis (CF). However, there is very little data on sleep in children and adolescents with CF and the association with severity of lung disease. A prospective study was conducted in CF children and age-matched controls. All patients completed sleep questionnaire and underwent an overnight polysomnographic study. Thirty-eight children and adolescents met the criteria for entry into the analysis, 24 children and adolescents with CF (S) and 14 controls (C). Sleep complaints were common in children and adolescents with CF; 43.5% reported sleep onset problem, 39.1% reported sleep maintenance problem, 30.4% were noted to snore at night, and 73.9% reported daytime sleepiness. Children and adolescents with CF had a significant decrease in sleep efficiency [SE; 75.2 +/- 2.5% (S) vs 85.6 +/- 1.7%(C); P < 0.01], prolonged rapid eye movement (REM) latency [150.5 +/- 16.6 min (S) vs 85.6 +/- 11.0 min (C); P < 0.05], and reduction in percentage of REM sleep [12.7 +/- 1.5% (S) vs 18.3 +/- 1.3% (C); P < 0.05]. The degree of sleep disruption as indicated by SE was correlated with forced expiratory volume in one second (FEV(1); r = 0.52, P < 0.05). However, there was no significant correlation between SE and minimum oxygen saturation [r = 0.30, P=not significant (NS)] or SE and maximal end-tidal pCO(2) (r = 0.11, P=NS). It is concluded that children and adolescents with CF have frequent sleep complaints and significant alteration in the sleep architecture. The magnitude of sleep disruption is associated with severity of lung disease, but is not directly correlated with the degree of nocturnal hypoxemia or hypoventilation. It is speculated that sleep disruption in children and adolescents with CF may have an impact on quality of life and clinical outcomes in this population.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 90%

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Sleep architecture in children and adolescents with cystic fibrosis and the association with severity of lung disease

et al. 2007

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“…The subjective sleep quality component score has been shown to be a robust predictor of outcomes across samples. 45,46 Memory functioning. Memory functioning was assessed using the Everyday Memory Questionnaire [EMQ 47,48 ].…”

Section: Participantsmentioning

confidence: 99%

HIV Medication Adherence and HIV Symptom Severity: The Roles of Sleep Quality and Memory

Babson

Heinz

Bonn‐Miller

2013

AIDS Patient Care and STDs

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The purpose of the current study was to examine the extent to which self-reported sleep quality, a clinically malleable factor, is associated with both HIV medication adherence and self-reported HIV symptom severity. In addition, we sought to examine whether sleep quality may explain the association between HIV medication adherence and symptom severity, as well as the role of self-reported memory functioning in terms of the above relations. This study took place from April 2010 to March 2012. Participants were 129 HIV-positive individuals who completed an ART pill count and series of structured clinical interviews and self-report questionnaires on sleep, memory, and HIV symptom severity. A series of regressions were conducted to test study hypotheses. After accounting for covariates (i.e., problematic alcohol, nicotine, and cannabis use, and mood disorder diagnosis), results indicated that self-reported sleep quality was associated with HIV medication adherence and selfreported HIV symptom severity, and that sleep quality partially mediated the relation between medication adherence and self-reported HIV symptom severity. In addition, memory functioning moderated the relation between self-reported sleep quality and HIV symptom severity, such that the interaction of poor sleep quality and relatively good memory functioning was associated with heightened self-reported HIV symptom severity. This study highlights the importance of assessing sleep and memory among HIV-infected individuals as they may represent treatment targets for those experiencing poor medication adherence or particularly severe HIV symptoms. Such information could lead to the inclusion of adjunct brief interventions to target sleep and memory functioning in order to reduce symptom severity among HIV-positive individuals with poor medication adherence.

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“…Similar to other obstructive lung diseases, hypoxemia during sleep is commonly seen in CF [30]. Patients with CF also commonly report poor sleep quality, and disruptions in sleep architecture have been observed on polysomnography [30,31]. There are several reported causes of disruption of sleep architecture in CF, including hypoxemia, cough, obstructive apneas, and pain [30,32,33].…”

Section: Cystic Fibrosismentioning

confidence: 99%

Respiratory medications and sleep

Bercovitch

Tsai

2012

Curr Respir Care Rep

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Respiratory physiology is affected by sleep. Patients with chronic lung disease often complain of poor sleep quality. Sleep disturbances may result from poor control of underlying lung disease, thereby disrupting sleep. Sleep disruption may result from hypoventilation resulting in worsened gas exchange. Sleep quality may also be affected by the respiratory medications used to treat certain lung diseases. These medications can have positive effects on sleep by providing better control of underlying respiratory abnormalities and therefore offering better sleep quality. These medications may also have undesirable side effects which can worsen sleep, such as hyperarousal resulting from corticosteroid use. Knowledge of medication effects on sleep is important in management of patients with underlying lung disease. As with all medications, it is important to balance potential benefits with possible negative side effects. This article discusses the effects of common medications used to treat respiratory diseases and their impact on sleep.

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Subjective sleep quality in cystic fibrosis

Cited by 66 publications

References 22 publications

Sleep architecture in children and adolescents with cystic fibrosis and the association with severity of lung disease

Sleep architecture in children and adolescents with cystic fibrosis and the association with severity of lung disease

HIV Medication Adherence and HIV Symptom Severity: The Roles of Sleep Quality and Memory

Respiratory medications and sleep

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