Subjectivity, psychosis and the science of psychiatry

Sass, Louis A.

doi:10.1002/wps.20986

Cited by 17 publications

(13 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Such consideration of empathic process has historically been a fundamental priority for schools of phenomenology and existential psychiatry, associated with the contributions of Karl Jaspers (Jaspers, 1968), Ludwig Binswanger (Binswanger, 1963), Rollo May (May et al, 1958), and others (Stanghellini et al, 2019). Recent reports highlighting the value of innovative methods based on principles of phenomenological psychiatry demonstrate current recognition of the value of process in patient-centered clinical care (Fusar-Poli et al, 2022; Sass, 2022).…”

Section: Discussionmentioning

confidence: 99%

Sociocultural Framework for Psychiatric Case Formulation

Weiss,

Deshmukh,

Sarmukaddam

et al. 2023

J Nerv Ment Dis

View full text Add to dashboard Cite

A Cultural Formulation Interview (CFI) field trial in India, widely reported racist violence in the United States, and casteist and religious communal conflicts in India highlighted inattention to structural issues affecting mental health problems in the Outline for Cultural Formulation (OCF) and the CFI in the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition). Consequently, we revised the OCF as a sociocultural formulation (SCF) to better consider structures of society and culture. We studied and compared clinicians' ratings of SCF case formulations from a constructed assessment instrument (SCF Interview [SCFI]) and the CFI. Socio-cultural formulations from SCFI interviews were rated higher for details of societal structural impact, and overall interrater agreement was better. CFI interviews were rated higher for clinical rapport. Revision of the CFI should enhance consideration of structural issues and incorporate them in SCFs that better integrate assessment process and case formulation content. The need to acknowledge structural sources of mental health problems is clear, and our study indicates how a sociocultural framework may be used for that.

show abstract

Section: Discussionmentioning

confidence: 99%

Sociocultural Framework for Psychiatric Case Formulation

Weiss,

Deshmukh,

Sarmukaddam

et al. 2023

J Nerv Ment Dis

View full text Add to dashboard Cite

show abstract

“…11 The disorder is characterized by a broad and di verse spectrum of clinical manifestations, including formal thought disorder, delusions, hallucinations, negative symp toms, and deficits in cognitive and social functioning. [12][13][14][15] Im portantly, although the reduction of symptom severity contrib utes to functional recovery, patients with remission of psychotic symptoms may still present serious impairment in different areas of reallife functioning, mainly because there are no effective treatments for major determinants of poor out comes such as negative symptoms and deficits in cognition. [16][17][18] Bipolar disorder is characterized by alternating and fluctu ating episodes of depression and mania or hypomania, or mixtures of manic and depressive features.…”

Section: Introductionmentioning

confidence: 99%

Advances in the understanding of the pathophysiology of schizophrenia and bipolar disorder through induced pluripotent stem cell models

Perrottelli,

Marzocchi,

Caporusso

et al. 2024

jpn

View full text Add to dashboard Cite

The pathophysiology of schizophrenia and bipolar disorder involves a complex interaction between genetic and environmental factors that begins in the early stages of neurodevelopment. Recent advancements in the field of induced pluripotent stem cells (iPSCs) offer a promising tool for understanding the neurobiological alterations involved in these disorders and, potentially, for developing new treatment options. In this review, we summarize the results of iPSC-based research on schizophrenia and bipolar disorder, showing disturbances in neurodevelopmental processes, imbalance in glutamatergic–GABAergic transmission and neuromorphological alterations. The limitations of the reviewed literature are also highlighted, particularly the methodological heterogeneity of the studies, the limited number of studies developing iPSC models of both diseases simultaneously, and the lack of in-depth clinical characterization of the included samples. Further studies are needed to advance knowledge on the common and disease-specific pathophysiological features of schizophrenia and bipolar disorder and to promote the development of new treatment options.

show abstract

“…As others have already argued on phenomenological grounds (Schwartz and Wiggins, 1985 ; Mullen, 2007 ; Parnas et al ., 2012 ; Nordgaard et al ., 2013 ; Sass, 2022 ), we believe that psychiatry's enduring tendency to conform to a philosophy of operationalism, at the expense of more genuinely pluralistic and multi-layered methodological enquiries into the person's subjectivity, may have become a self-sustaining form of stagnation and impediment to the generation of new knowledge. In line with other recent calls for more phenomenology in psychiatry (Larsen et al ., 2022 ), we believe that phenomenological concepts and methods can act as a fruitful corrective for contemporary psychiatry – with the proviso that a stance of openness, provisionality and humility is adopted (Ritunnano et al ., 2022a ).…”

Section: Introduction: Why Do We Need Phenomenology In Psychiatry?mentioning

confidence: 99%

Phenomenology as a resource for translational research in mental health: methodological trends, challenges and new directions

Ritunnano

Papola

Broome

et al. 2023

Epidemiol Psychiatr Sci

View full text Add to dashboard Cite

This editorial reflects on current methodological trends in translational research in mental health. It aims to build a bridge between two fields that are frequently siloed off from each other: interventional research and phenomenologically informed research. Recent years have witnessed a revival of phenomenological approaches in mental health, often – but not only – as a means of connecting the subjective character of experience with neurobiological explanatory accounts of illness. Rich phenomenological knowledge accrued in schizophrenia, and wider psychosis research, has opened up new opportunities for improving prediction, early detection, diagnosis, prognostic stratification, treatment and ethics of care. Novel qualitative studies of delusions and hallucinations have challenged longstanding assumptions about their nature and meaning, uncovering highly complex subjective dimensions that are not adequately captured by quantitative methodologies. Interdisciplinary and participatory research efforts, informed by phenomenological insights, have prompted revisions of pre-established narratives of mental disorder dominated by a dysfunction framework and by researcher-centric outcome measures. Despite these recent advances, there has been relatively little effort to integrate and translate phenomenological insights across applied clinical research, with the goal of producing more meaningful, patient-valued results. It is our contention that phenomenological psychopathology – as the basic science of psychiatry – represents an important methodology for advancing evidence-based practices in mental health, and ultimately improving real-world outcomes. Setting this project into motion requires a greater emphasis on subjectivity and the structures of experience, more attention to the quality and patient-centredness of outcome measures, and the identification of treatment targets that matter most to patients.

show abstract

Subjectivity, psychosis and the science of psychiatry

Cited by 17 publications

References 9 publications

Sociocultural Framework for Psychiatric Case Formulation

Sociocultural Framework for Psychiatric Case Formulation

Advances in the understanding of the pathophysiology of schizophrenia and bipolar disorder through induced pluripotent stem cell models

Phenomenology as a resource for translational research in mental health: methodological trends, challenges and new directions

Contact Info

Product

Resources

About