Submaximal Exercise Testing: Clinical Application and Interpretation

Noonan, Vanessa K.; Dean, Elizabeth

doi:10.1093/ptj/80.8.782

Cited by 491 publications

(316 citation statements)

References 74 publications

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“…We performed a unique study that objectively investigated different 47 To date, one other survivors' study assessed submaximal endurance using the 6 MWT and found no difference in scores between a group of 49 survivors of NBL and WT versus controls. 22 Our study seems to support these findings.…”

Section: Discussionmentioning

confidence: 99%

Health‐related fitness in very long‐term survivors of childhood cancer: A cross‐sectional study

Hartman

Pluijm

Wijnen

et al. 2017

Pediatric Blood & Cancer

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Section: Discussionmentioning

confidence: 99%

Health‐related fitness in very long‐term survivors of childhood cancer: A cross‐sectional study

Hartman

Pluijm

Wijnen

et al. 2017

Pediatric Blood & Cancer

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“…Submaximal exercise testing has been reported as a safe, simple, and well‐tolerated estimate of V O 2max and functional ability in children with chronic disease (20, 22–25). Giannini and Protas (24) showed that children with arthritis had higher submaximal HR and trended towards higher V O 2submax than healthy peers, suggesting significantly lower submaximal efficiency.…”

Section: Discussionmentioning

confidence: 99%

“…However, V O 2peak may be an inappropriate outcome measure in groups with significant limitations. Instead, submaximal VO 2 (V O 2submax ) may be used as a predictor of V O 2max or as an independent measure of performance in standardized activities (18, 20–23). Giannini and Protas (24) reported that children with JIA had higher submaximal heart rate (HR) and tended towards higher V O 2submax (higher oxygen requirement) as compared with matched controls during a bicycle task.…”

Section: Introductionmentioning

confidence: 99%

The effects of vigorous exercise training on physical function in children with arthritis: A randomized, controlled, SINGLE‐BLINDED trial

Singh‐Grewal¹,

Schneiderman‐Walker²,

Wright³

et al. 2007

Arthritis & Rheumatism

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Objective. To examine the effectiveness of high-intensity aerobic training compared with low-intensity training in terms of energy cost of locomotion, peak oxygen uptake, peak power, and self-reported physical function in children with juvenile idiopathic arthritis (JIA). Methods. Eighty children with JIA, ages 8 -16 years, were enrolled in a randomized, single-blind controlled trial. Both groups participated in a 12-week, 3-times-weekly training program consisting of high-intensity aerobics in the experimental group and qigong in the control group. Subjects underwent exercise testing measuring submaximal oxygen uptake at 3 km/hour (VO 2submax ) as the primary outcome, maximal oxygen uptake, and peak power at the beginning and end of the program. Physical function was measured using the Child Health Assessment Questionnaire (C-HAQ). Results. The exercise program was well tolerated in both groups. There was no difference in VO 2submax or any other exercise testing measures between the groups through the study period and no indication of improvement. Both groups showed significant improvements in C-HAQ with no difference between the groups. Adherence was higher in the control group than the experimental group. Conclusion. Our findings suggest that activity programs with or without an aerobic training component are safe and may result in an important improvement in physical function. The intensity of aerobic training did not seem to provide any additional benefits, but higher adherence in the qigong program may suggest that less intensive regimens are easier for children with JIA to comply with, and provide a degree of benefit equivalent to more intensive programs.

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“…3 Physical fitness is typically expressed as cardiorespiratory fitness (CRF) and is assessed by exercise tolerance testing. 4 cardiac and respiratory functioning. Directly measured VO 2 max, an objective and quantitative measure of CRF, is a gold standard for assessing the amount of oxygen consumption during exercise testing.…”

Section: Introductionmentioning

confidence: 99%

Cardiorespiratory fitness and risk of heart failure: a population‐based follow‐up study

Khan

Kunutsor

Rauramaa

et al. 2013

European J of Heart Fail

119

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Aim To examine the relationship between cardiorespiratory fitness (CRF) and risk of incident heart failure (HF). Methods and results Cardiorespiratory fitness, as measured by maximal oxygen uptake (VO2max), was assessed at baseline in a prospective cohort of 1873 men aged 42–61 years without HF or chronic respiratory disease. During a mean follow‐up of 20.4 years, 152 incident HF events were recorded. Within‐person variability was calculated using data from repeat measurements taken 11 years apart. The age‐adjusted hazard ratio (HR) per unit increase (1 mL/kg/min of VO2max) in CRF was 0.89 [95% confidence interval (CI) 0.86–0.93], which was minimally attenuated to 0.94 (95% CI 0.90–0.98) after further adjustment for established HF risk factors (body mass index, systolic blood pressure, history of cardiovascular disease, diabetes, heart rate, and LV hypertrophy) and incident coronary events as a time‐varying covariate. In a comparison of extreme quartiles of CRF levels (VO2max ≥35.4 vs. ≤25.7 mL/kg/min), the corresponding HRs were 0.27 (0.15–0.50) and 0.48 (0.25–0.92), respectively. Each 1 MET (metabolic equivalent of oxygen consumption) increment in CRF was associated with a 21% (7–33%) reduction in multivariable adjusted risk of HF. Addition of CRF to a HF risk prediction model containing established risk factors did not significantly improve risk discrimination (C‐index change = 0.0164, P = 0.07). Conclusions In this Finnish population, there is a strong, inverse, and independent association between long‐term CRF and HF risk, consistent with a dose–response relationship. The protective effect of CRF on HF risk warrants further evaluation.

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Submaximal Exercise Testing: Clinical Application and Interpretation

Cited by 491 publications

References 74 publications

Health‐related fitness in very long‐term survivors of childhood cancer: A cross‐sectional study

Health‐related fitness in very long‐term survivors of childhood cancer: A cross‐sectional study

The effects of vigorous exercise training on physical function in children with arthritis: A randomized, controlled, SINGLE‐BLINDED trial

Cardiorespiratory fitness and risk of heart failure: a population‐based follow‐up study

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