“…We point out that, though experimental design is a classical problem in the statistical literature [34,20,62], it is only very recently that interests in computationally efficient experimental design algorithms began to arise in the computer science community [15,7,58,86,1,2]. Most experimental design algorithms, based on various types of optimality criteria including but not limited to A(verage)-, D(eterminant)-, E(igen)-, V(ariance)-, G-optimality and Bayesian alphabetical optimality, are NP-hard computational in their exact form [23,19], with the only exception of T(race)-optimality which is trivial to solve.…”