Subphase pH effect on the limiting molecular area of amphiphilic β-diketones in Langmuir monolayers

Devterova, Julia; Соколов, М. Е.; Buz’ko, V. Yu.; Repina, I. N.; Rudnov, Peter S.; Panyushkin, V. T.

doi:10.1016/j.mencom.2020.07.034

Cited by 10 publications

(4 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, the LBF consisting of the destroyed complexes and the free ligand is transferred to the substrate. This assumption was confirmed by our studies [20][21][22][23]. In this regard, when obtaining LBFs based on CCs, it is necessary to pay special attention to the effect of the composition of the subphase (concentration of the complexing agent ion, pH, etc.)…”

Section: Introductionsupporting

confidence: 78%

Features of the Preparation and Luminescence of Langmuir-Blodgett Films Based on the Tb(III) Complex with 3-Methyl-1-phenyl-4-stearoylpyrazol-5-one and 2,2′-Bipyridine

et al. 2022

View full text Add to dashboard Cite

In this study, we investigated the effect of terbium ions (Tb3+) on the subphases of the limiting area of the molecule for the complex compound (CC) TbL3∙bipy (where HL is 3-methyl-1-phenyl-4-stearoylpyrazol-5-one and bipy is 2,2’-bipyridine). We examined the Langmuir monolayer and the change in the luminescence properties of TbL3∙bipy-based Langmuir-Blodgett films (LBFs). The analysis of the compression isotherms, infrared, and luminescence spectra of TbL3∙bipy LBFs was performed by varying the concentration of Tb3+ in the subphases. Our results demonstrate the partial dissociation of the CC at concentrations of C(Tb3+) < 5 × 10−4 M.

show abstract

Section: Introductionsupporting

confidence: 78%

Features of the Preparation and Luminescence of Langmuir-Blodgett Films Based on the Tb(III) Complex with 3-Methyl-1-phenyl-4-stearoylpyrazol-5-one and 2,2′-Bipyridine

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In addition, there are two characteristic parameters, respectively, the liftoff area

(the molecular occupation area where the isotherm rise just emerges related to the baseline) and the limiting area

(an empirical parameter approximating the mean molecular cross sectional area) [ 28 , 29 ]. The

value is conventionally given from the

isotherms by extrapolating the slope of isotherm in its steepest range to the zero-surface pressure [ 35 ], if a liquid-condensed or solid phase is observed in the isotherm.…”

Section: Resultsmentioning

confidence: 99%

Influence of InP/ZnS Quantum Dots on Thermodynamic Properties and Morphology of the DPPC/DPPG Monolayers at Different Temperatures

et al. 2023

View full text Add to dashboard Cite

In this work, the effects of InP/ZnS quantum dots modified with amino or carboxyl group on the characteristic parameters in phase behavior, elastic modulus, relaxation time of the DPPC/DPPG mixed monolayers are studied by the Langmuir technology at the temperature of 37, 40 and 45 °C. Additionally, the information on the morphology and height of monolayers are obtained by the Langmuir–Bloggett technique and atomic force microscope technique. The results suggest that the modification of the groups can reduce the compressibility of monolayers at a higher temperature, and the most significant effect is the role of the amino group. At a high temperature of 45 °C, the penetration ability of InP/ZnS-NH2 quantum dots in the LC phase of the mixed monolayer is stronger. At 37 °C and 40 °C, there is no clear difference between the penetration ability of InP/ZnS-NH2 quantum dots and InP/ZnS-COOH quantum dots. The InP/ZnS-NH2 quantum dots can prolong the recombination of monolayers at 45 °C and accelerate it at 37 °C and 40 °C either in the LE phase or in the LC phase. However, the InP/ZnS-COOH quantum dots can accelerate it in the LE phase at all temperatures involved but only prolong it at 45 °C in the LC phase. This work provides support for understanding the effects of InP/ZnS nanoparticles on the structure and properties of cell membranes, which is useful for understanding the behavior about the ingestion of nanoparticles by cells and the cause of toxicity.

show abstract

“…The mean molecular area is called the liftoff area

when the

isotherm increases from the baseline. The limiting area

can be calculated by extrapolating the slope of the isotherm in its steepest range to the zero-surface pressure ( Devterova et al, 2020 ), which is an empirical parameter around the mean molecular cross-sectional area. At the high surface pressure of the isotherm, with increasing surface pressure, the mean molecular area suddenly decreases, indicating that the monolayer has collapsed.…”

Section: Resultsmentioning

confidence: 99%

Effect of high sodium ion level on the interaction of AmB with a cholesterol-rich phospholipid monolayer

Wang,

Qiang,

et al. 2024

Front. Mol. Biosci.

View full text Add to dashboard Cite

Invasive fungal infections are a primary reason for high mortality in immunocompromised people, especially in critically ill patients, such as intensive care unit (ICU) patients, advanced cancer patients, or severe burn patients. Hypernatremia also can increase mortality in severely ill patients. Amphotericin B (AmB) is the gold standard for treating infections, but in severely ill patients, AmB can cause hematotoxicity when administered intravenously due to its interaction with cholesterol on red blood cell membranes. This results in limited doses of AmB and affects the treatment of infections. The proportion of cholesterol molecules in membrane lipids in red blood cells is as high as 50 mol%, and the sodium ions can influence the interaction between AmB and lipids on the membrane. Therefore, in the complex clinical situation of a severely ill patient with a fungal infection and hypernatremia, the interaction between amphotericin B and the red blood cell membranes is worth studying in depth. In this work, the interaction between AmB and the dipalmitoyl phosphatidylcholine (DPPC)/cholesterol mixed monolayer in the presence of high sodium ion levels was studied when the proportion of cholesterol was 50%. The results show that the effect of AmB on reducing the monolayer’s area at a high level of sodium ions is slightly stronger at 30 mN/m. The effect of AmB on reducing the elastic modulus of the DPPC/Chol monolayer is significantly weakened by a high sodium ion level, compared with the level of sodium ions at normal physiological concentration. The higher the sodium ion concentration, the weaker the intermolecular force of the DPPC/Chol/AmB mixed monolayers. The scanning electron microscope (SEM) and atomic force microscopy (AFM) observations suggest that at a high sodium ion level, the presence of AmB significantly reduces the surface roughness of the DPPC/Chol monolayer. AmB may bind to cholesterol molecules, and it isolates cholesterol from the monolayer, resulting in a reduced height of the cholesterol-rich monolayer and an increasingly dispersed monolayer region. The results are beneficial to understanding the mechanism of impact of a high sodium ion level on the relationship between AmB and red blood cell membranes rich in cholesterol and are valuable for understanding the hemolytic toxicity of AmB to red blood cells at a high sodium ion level.

show abstract

Subphase pH effect on the limiting molecular area of amphiphilic β-diketones in Langmuir monolayers

Cited by 10 publications

References 16 publications

Features of the Preparation and Luminescence of Langmuir-Blodgett Films Based on the Tb(III) Complex with 3-Methyl-1-phenyl-4-stearoylpyrazol-5-one and 2,2′-Bipyridine

Features of the Preparation and Luminescence of Langmuir-Blodgett Films Based on the Tb(III) Complex with 3-Methyl-1-phenyl-4-stearoylpyrazol-5-one and 2,2′-Bipyridine

Influence of InP/ZnS Quantum Dots on Thermodynamic Properties and Morphology of the DPPC/DPPG Monolayers at Different Temperatures

Effect of high sodium ion level on the interaction of AmB with a cholesterol-rich phospholipid monolayer

Contact Info

Product

Resources

About