Subsequent fertility in women who undergo cardiac surgery

Nunley, Wallace C.; Kolp, Lisa A.; Dabinett, L. N.; Kitcbin, James D.; Bateman, Bruce G.; Craddock, George B.

doi:10.1016/0002-9378(89)90358-x

Cited by 6 publications

(2 citation statements)

References 10 publications

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“…In 1963, Mortensen and Ellsworth [8] reported on an incidence of 3.6% of involuntary sterile women following cardiac surgery, while Nunley et al [9] stated that the inci dence of infertility was 7.3% after cardiac surgery in a study published in 1989.…”

Section: Discussionmentioning

confidence: 99%

Influence of Valve Surgery on Female Fertility

Rosen

Klein²,

Rosen³

et al. 1992

Gynecol Obstet Invest

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Pregnancies following cardiac valve surgery represent a considerable maternal and fetal risk. The present paper is a report of 163 women in child-bearing age who underwent cardiac valve surgery. Congenital (14.7%) and acquired (85.3%) cardiac defects required a total of 72 alloplastic and 16 bioprosthetic valve implantations. In 69 patients, purely instrumental correction was performed, in 6 patients conduits were placed. Thirty-four pregnancies were observed and led to the delivery of 18 healthy infants. The birth weight was always in the 2-sigma normal range or slightly above. Three cesarean sections were performed due to the cardiac defect, in 6 patients vacuum extraction or forceps delivery was done, and in 9 patients delivery was spontaneous. We observed 4 cases of spontaneous abortion, and in 12 cases interruption of pregnancy. 75.1 % women never became pregnant. Potential risks in terms of endocarditis, repeated valve implantation and anticoagulation are emphasized, methods to decrease the physical strain during delivery are discussed.

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Section: Discussionmentioning

confidence: 99%

Influence of Valve Surgery on Female Fertility

Rosen

Klein²,

Rosen³

et al. 1992

Gynecol Obstet Invest

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“…It has been confirmed that women with cardiac diseases could have better reproductive outcomes because of the mature management of cardiac diseases during pregnancy. 6,25) The subsequent childbearing performance of women after cardiac surgeries was first noticed by Nunley et al, 26) who suggested that cardiac surgeries requiring cardiopulmonary bypass were more likely to discourage women from making childbearing decisions.…”

Section: Childbearing Performances After MV Interventionsmentioning

confidence: 99%

Childbearing Performances and Outcomes of Female Patients with Rheumatic Mitral Valve Diseases after Different Mitral Interventions

Zhao

et al. 2023

ATCS

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Purpose: This study aimed to illustrate how percutaneous balloon mitral valvuloplasty (PBMV) and mitral valve (MV) surgeries influence women of childbearing age with rheumatic mitral valve diseases (RMVDs) from two aspects, including clinical outcomes and their postoperative childbearing performances. Methods: Female patients with RMVD who were of childbearing age and underwent MV interventions between 2007 and 2019 at Beijing Anzhen Hospital were identified. Outcomes included all-cause deaths, repeated MV interventions, and atrial fibrillation. A survey about childbearing attempts and complications during pregnancy was also performed during follow-up. Results: A total of 379 patients were involved in this study, consisting of 226 cases of mitral valve replacements, 107 cases of mitral valve repairs (MVrs), and 46 cases of PBMVs. PBMV was associated with higher possibilities of repeated MV interventions (P <0.05). Postoperative childbearing attempts were more frequently observed among bioprosthesis, MVr, and PBMV (P <0.05). However, PBMV and MVr showed a higher incidence of cardiac complications during pregnancy as compared to prosthesis replacement (P <0.05). Conclusions: MVr and PBMV are not recommended to young female patients for higher incidences of postoperative complications. Safe pregnancy is more likely to be present among patients with biological prosthesis.

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