Subsequent pancreatitis and haemothorax in a patient of expanded dengue syndrome

Anam, Ahmad Mursel; Rabbani, Raihan; Shumy, Farzana; Polash, Mohammad Mufizul Islam

doi:10.1177/0049475515594084

Cited by 14 publications

(10 citation statements)

References 3 publications

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“…ARDS in dengue is due to increased permeability of alveolar capillary membrane, which results in alveolar edema leading to pulmonary dysfunction [21]. Anam et al [22] had an unusual EDS case presenting as pancreatitis and haemothorax with respiratory distress. This complication requires early recognition and prompt management for favorable outcome.…”

Section: Discussionmentioning

confidence: 99%

Clinical Profiles of Dengue Infection during an Outbreak in Northern India

Laul

Merugumala

et al. 2016

Journal of Tropical Medicine

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Introduction. Dengue fever is an arboviral disease, which is transmitted by mosquito vector and presents as varied clinical spectrum of dengue fever (DF), dengue hemorrhagic fever (DHF), dengue shock syndrome (DSS), and expanded dengue syndrome (EDS) with atypical presentations, thus posing a diagnostic dilemma. Unless we are aware of these presentations, diagnosis as well as early initiation of treatment becomes difficult. We studied the various clinical presentations of dengue infection during an outbreak of disease in 2015. Materials and Methods. A total of 115 confirmed cases of dengue infection from Department of Medicine of Deen Dayal Upadhyay Hospital, New Delhi, were enrolled in this observational study. Results. The common signs and symptoms of dengue infection were fever, headache, body ache, backache, retro-orbital pain, bleeding manifestations, and rash in 100%, 87%, 86%, 58%, 41%, 21%, and 21%, respectively. Nonspecific or warning signs and symptoms included vomiting, weakness, abdominal pain, breathlessness, vertigo, sweating, and syncope. Other possible signs and symptoms of coinfections, comorbidities, or complications included diarrhea, sore throat, and neurological manifestations. There were seven patients with coinfections and four with comorbidities. The final diagnosis of these patients was DF (73%), DHF (16.5%), DSS (1.7%), and EDS (4.3%). Among EDS patients, the atypical presentations included encephalopathy, lateral rectus nerve palsy, acalculous cholecystitis, and myocarditis. Four patients required ICU care and there was no death in this study. Conclusion. Knowledge of atypical presentations is a must for early diagnosis and timely intervention to prevent life-threatening complications.

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Section: Discussionmentioning

confidence: 99%

Clinical Profiles of Dengue Infection during an Outbreak in Northern India

Laul

Merugumala

et al. 2016

Journal of Tropical Medicine

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“…There have been reports of cases with bloody pleural effusion. [6][7][8] However, in this case, the patient presented at the end of febrile phase. And as he went through his critical phase he developed pleural effusion which was found to be hemothorax.…”

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confidence: 72%

Unprovoked hemothorax : an unusual presentation in Dengue Haemorrhagic Fever

Manappallil

2016

Asian J Med Sci

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A B S T R A C TAccording to WHO, Dengue fever (DF) is the most rapidly spreading mosquito-borne viral disease in the world. Dengue Haemorrhagic fever (DHF) is a severe and more serious form of DF, characterised by fever, bleeding manifestations, plasma leakage and thrombocytopenia. This is a case of a 28 year old male, who presented with history of fever and myalgia and was diagnosed to have DF. He had developed acute onset dyspnoea and his chest X-Ray showed right sided pleural effusion. Pleurocentesis revealed haemorrhagic fluid in the absence of trauma.Unprovoked hemothorax as an initial presentation of DHF has rarely been reported.

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“…The exact pathogenesis of acute pancreatitis in DHF is likewise poorly understood, but thought to result either from direct invasion by the virus itself, causing inflammation and destruction of pancreatic acinar cells, or pancreatic damage due to dengue shock syndrome (grades III and IV of DHF), or acute viral infection causing an autoimmune response to pancreatic islet cells and development of oedema of the ampulla of Vater with obstruction to the outflow of pancreatic fluid. 3…”

Section: Discussionmentioning

confidence: 99%

Expanded dengue syndrome: three concomitant uncommon presentations in the same patient

2017

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We report a case of expanded dengue syndrome, where three uncommon presentations occurred concomitantly. A patient with dengue haemorrhagic fever presented initially with acute acalculous cholecystitis along with acute pancreatitis, but later on, during resolution of pancreatitis and cholecystitis, developed pancytopenia, most likely due to haemophagocytic syndrome. Such presentations, besides being rare themselves, have not been reported to occur concomitantly, in the same patient, during the same disease process.

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Subsequent pancreatitis and haemothorax in a patient of expanded dengue syndrome

Cited by 14 publications

References 3 publications

Clinical Profiles of Dengue Infection during an Outbreak in Northern India

Clinical Profiles of Dengue Infection during an Outbreak in Northern India

Unprovoked hemothorax : an unusual presentation in Dengue Haemorrhagic Fever

Expanded dengue syndrome: three concomitant uncommon presentations in the same patient

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