Subserous Jejunal Haemorrhages During Mecamylamine Therapy

Pempidine for Hypertension

“…Patients with ileus due to mecamylamine have been unsuspectingly exposed to the risk of laparotomy (Grant and Boyd, 1957). Intestinal haemorrhage has been reported (Addison and Towers, 1959) and psychosis and incoordination, due to its accumulation within the brain, are known to occur (Schneckloth et al, 1956;Harington and Kincaid-Smith, 1958;Hickish, 1958;Hift, 1958;Connor, 1958;Somers and Gitau, 1959). In contrast, pempidine has a shorter duration of action.…”