2001
DOI: 10.1016/s0167-0115(00)00233-0
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Substance P (NK1) receptor in relation to substance P innervation in rat duodenum after irradiation

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Cited by 13 publications
(5 citation statements)
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“…Other group of authors 43 observed changes in SP receptor expression during the chronic intestinal inflammation and suggested that SP receptors are a potential target for therapeutic regulation of the inflammatory responses. Also, Höckerfelt et al 44 observed an interaction between the SP-containing nerve fibers and mast cells in the irradiation provoked tissue responses in duodenum of rat. By using another model of the experimental infection, Balemba et al 36 suggested that the alterations in VIP and SP immunoreactivities correlate to pathological lesions and severity of inflammation in the large intestine of pigs infected with S. japonicum .…”
Section: Discussionmentioning
confidence: 96%
“…Other group of authors 43 observed changes in SP receptor expression during the chronic intestinal inflammation and suggested that SP receptors are a potential target for therapeutic regulation of the inflammatory responses. Also, Höckerfelt et al 44 observed an interaction between the SP-containing nerve fibers and mast cells in the irradiation provoked tissue responses in duodenum of rat. By using another model of the experimental infection, Balemba et al 36 suggested that the alterations in VIP and SP immunoreactivities correlate to pathological lesions and severity of inflammation in the large intestine of pigs infected with S. japonicum .…”
Section: Discussionmentioning
confidence: 96%
“…The dynamic changes in the amount of SP in this study were in accordance with the distribution of the NK-1R on cutaneous wounds, as reported. 17 The tissue levels of SP may be related to the healing ability of the wounds.…”
Section: Discussionmentioning
confidence: 99%
“…In the intestine, NK1-R has variably been shown for smooth muscle cells, blood vessel walls, epithelial cells, neurons in the intestinal plexuses, the interstitial cells of Cajal and in inflammatory cells (e.g. [20,38,40,45,46]). It is thus evident that NK1-R can have different roles in different tissues.…”
Section: Discussionmentioning
confidence: 99%