Substance use during pregnancy

Forray, Ariadna

doi:10.12688/f1000research.7645.1

Cited by 223 publications

(177 citation statements)

References 124 publications

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“…Higher rates of breastfeeding among Swedish women (33–35) may play a role in this, as breastfeeding appears to be protective against relapse to alcohol (36) and cigarette smoking (37). Klee has previously reviewed the wide range of factors that might contribute to a protective effect of parenting on drug abuse (38).…”

Section: Discussionmentioning

confidence: 99%

The Protective Effect of Pregnancy on Risk for Drug Abuse: A Population, Co-Relative, Co-Spouse, and Within-Individual Analysis

Kendler

Svikis

Sundquist

et al. 2017

AJP

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Objective To determine whether pregnancy is an intrinsic motivator for drug abuse (DA) cessation. Method We conducted, in Swedish females born 1980–1990 who gave birth at ages 20–35 (N=149,512), prospective cohort, co-relative, co-spouse, and within-person analyses of registration for DA during pregnancy. DA was assessed from medical, criminal and pharmacy registries. Results In the population, rates of DA were lower during pregnancy (unadjusted OR=0.67, 95% CIs 0.60–0.74). Compared to population results, the negative association between pregnancy and DA was moderately stronger in cousins (OR=0.49, 0.39–0.62) and substantially stronger in siblings (OR=0.35, 0.24–0.51) discordant for pregnancy. The estimated OR for DA in pregnancy-discordant monozygotic twins was even stronger: 0.17 (0.10–0.31). Within-individuals, the OR for DA while pregnant compared to an equivalent pre-pregnancy interval was similar to that seen in pregnancy-discordant monozygotic twins: 0.22 (0.19–0.26). Compared to cohabiting fathers, mothers had a greater reduction in risk for DA during pregnancy (OR=0.40, 0.34–0.47). Pregnancy was more protective in those with low parental education and without a cohabiting actively drug abusing father. Compared to pre-pregnancy baseline, within-individual analyses indicate risk for DA is also substantially reduced post-partum e.g. day 0–242 OR=0.13 (0.11–0.16). Conclusions Risk for DA in women is substantially reduced during pregnancy. Multiple analyses suggest that this association is largely causal, suggesting that pregnancy is indeed a strong intrinsic motivator for DA cessation. Similar strong protective effects may be present immediately post-partum. Our results have implications for our etiologic models of DA and especially for contingency management programs seeking to reduce DA risk.

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Section: Discussionmentioning

confidence: 99%

The Protective Effect of Pregnancy on Risk for Drug Abuse: A Population, Co-Relative, Co-Spouse, and Within-Individual Analysis

Kendler

Svikis

Sundquist

et al. 2017

AJP

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“…Another parameter not available in a number of studies is socioeconomic status (SES) which is known related to alcohol consumption patterns [139]. The concurrent consumption of alcohol and other drugs, such as marijuana or nicotine, is rather common [140], and while some studies (for example, see [47]. Vermis hypoplasia was observed in children born to mothers who had consumed alcohol in the first trimester, in the first two trimesters, as well as throughout gestation [47].…”

Section: Insights From Radiological Studies Of Humans With Fasdmentioning

confidence: 99%

Radiological studies of fetal alcohol spectrum disorders in humans and animal models: An updated comprehensive review

Nguyen

Chong

Tieng

et al. 2017

Magnetic Resonance Imaging

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“…Data on consumption of illicit substances during pregnancy are lacking for the majority of low- and middle-income countries, according to the World Health Organization. Research indicates that cannabis is the most common illicit drug worldwide, followed by amphetamine-type stimulants and opioids, and as such, may be more likely to be used by reproductive-aged women (Forray, 2016). In contrast, the most prevalent drugs in this study were inhalants and crack.…”

Section: Discussionmentioning

confidence: 99%

History of child sexual abuse among women consuming illicit substances in Mexico City

Mendoza-Meléndez

Cepeda

Frankeberger

et al. 2018

Journal of Substance Use

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Introduction: Child sexual abuse (CSA) is a pervasive problem that has been linked to numerous developmental, social, health, and substance use consequences. Nevertheless, the relationship between CSA and the consumption of psychoactive substances has not been adequately studied in Mexico. The present study aims to examine this association between history of CSA and illicit substance use and associated risk behaviors in a sample of young adult women in Mexico City. Design and Methods: The present study uses a cross-sectional design to examine sexual abuse history among women who use illicit substances. Data collection consisted of a questionnaire administered through face-to-face interviews with 101 women who sought treatment for substance use in Mexico City. A bivariate analysis was used to examine women who experienced sexual abuse and those who did not. Odds ratio and relative risk were estimated. Results: A total of 101 women were interviewed with an average age of 19.2 years. The average age of onset of drug use was 15.4 years. Among participants, 68% reported having been victims of sexual abuse and rape. The average age of reported sexual abuse was 12.2 years. Participants reported a high rate of polydrug use (32.7%), consuming more than two drugs. Sexual abuse was associated with detention by police for drugs, forced prostitution, and consumption of substances during pregnancy. Discussion and conclusions: This study found that sexual abuse and rape were highly associated with substance abuse outcomes and associated risk behaviors.

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Substance use during pregnancy

Cited by 223 publications

References 124 publications

The Protective Effect of Pregnancy on Risk for Drug Abuse: A Population, Co-Relative, Co-Spouse, and Within-Individual Analysis

The Protective Effect of Pregnancy on Risk for Drug Abuse: A Population, Co-Relative, Co-Spouse, and Within-Individual Analysis

Radiological studies of fetal alcohol spectrum disorders in humans and animal models: An updated comprehensive review

History of child sexual abuse among women consuming illicit substances in Mexico City

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