Substrate and Product Selective Supramolecular Catalysis by Pillar[5]arene in the Alkylation of Primary Linear Amines with Allyl Bromide
Chiara Buranello,
Marta Da Pian,
Tommaso Lorenzetto
et al.
Abstract:We report the supramolecular catalysis exerted by the
cavity of
pillar[5]arene on the classic nucleophilic substitution reaction of
primary alkyl amines on allyl bromide. The tubular nanocatalyst imparts
both substrate selectivity for linear amines and product selectivity
in favor of secondary amine products. The reaction turned out to be
very sensitive to the size of the cavity and the nature of the alkoxy
residues on the rim of the cylindrical nanometric catalyst. The acceleration
observed was due to the sta… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.