Subungual Metastasis of an Adenocarcinoma of the Prostate in a Finger

Abstract

Cutaneous metastasis is a rare event occurring most frequently in patients previously diagnosed with cancer. However, subungual metastases are even less frequent. The most common neoplasms associated with the latter are lung, kidney, and breast neoplasms. Lung cancer is the main cause of subungual metastases in the fingers, and genitourinary tract tumors are the main cause of subungual metastases in the toes. This is the first case report of an adenocarcinoma of the prostate with subungual metastasis.

Subungual Metastasis from Ovarian Cancer: Case Report and Brief Review of the Literature

“…SM, defined as the presence of metastatic malignant cells under the nail plate, in the nail bed and the tissues around it, is estimated to account for 1% of all acrometastases and 0.1% of cutaneous metastases [1][2][3][4]. SM more frequently occurs in a patient with a personal history positive for a solid or hematologic cancer, but rarely it is the presenting sign of an undiagnosed cancer [5].…”

“…SM more frequently occurs in the digits of the hands than of the feet and in most cases affects only one finger, with a predilection for the thumb, even though involvement of multiple digits is reported [3, 4]. Men seem to be more affected than women, while there is no evidence of a prevalence of one side of the body with respect to the other [5].…”

“…Dermoscopy of SM has been reported only once and had analogies with our case. It showed nonmelanocytic black pigmentation of the nail bed, with hematomas and vascular-like nodules, as well as dilated blood vessels [3]. Dermoscopy is not specific, but it appears to be characterized by a variegated vascular pattern.…”

<p>Rare Site Hepatocellular Carcinoma Metastasis</p>

“…Only three cases can be found in the literature: from a rectal cancer, 18 from renal carcinoma 19 and from prostate cancer. 20 After analyzing the RSHM cases including ours (Table 1), we intended to answer the previous questions.…”