“…The multifactorial nature of thoracic pain, along with the "opioid epidemic" and opioids' side effects, has prompted a "paradigm shift" in thoracic anaesthesia, incorporating multimodal analgesia and opioid-free anaesthesia protocols [7,10]. Opioidfree anaesthesia may also enhance return to baseline function in thoracic surgery patients [13]. In our case the joint decision pathway resulted in an open, non-intubated lung resection under exclusively intravenous opioid-sparing analgesia and sedation.…”