Background: Minimally invasive techniques are becoming increasingly popular in thoracic surgery.Although median sternotomy is the traditional approach for thymectomy, video-assisted thoracoscopic surgery (VATS) approaches now predominate. This study reports a case series of the novel uniportal subxiphoid-VATS approach to extended thymectomy.Methods: Over the period of study (October 2014-January 2017) 17 patients underwent uniportal subxiphoid-VATS extended thymectomy for a thymic nodule at the Shanghai Pulmonary Centre. Ten patients were female, and the mean age of the cohort was 55 years. The mean size of nodule was 23.6 mm.Results: The mean operative duration was 2.5 hours, with one conversion to thoracotomy for bleeding.The mean operative blood loss was 115 mL. The median length of hospital stay was 4 days. There were no episodes of phrenic nerve palsies. The 30-day survival was 100%.Conclusions: Uniportal subxiphoid-VATS is a feasible and safe surgical approach to extended thymectomy in selected patients, with good post-operative outcomes. Here we present a case series of subxiphoid-VATS thymectomies describing intra and post-operative characteristics that demonstrate the safety and feasibility of this novel surgical approach.
MethodsAll procedures were performed in Shanghai Pulmonary Hospital, Shanghai, China, between October 2014 and January 2017.Exclusion criteria for subxiphoid-VATS thymectomy included:(I) thymic tumour, stage II-IV (macroscopic spread to surrounding fatty tissue or beyond, including distal metastases); (II) body mass index >30; (III) cardiomegaly, poor cardiac function or severe arrhythmia (because of reduced operative access to left-side of thymus and risk of cardiovascular compromise).
Surgical techniqueUnder general anaesthesia, patients were placed in a supine position with a roll beneath the scapulae (for maximal chest extension). Selective one lung ventilation was used during the procedure. A 4-cm-long horizontal subxiphoid incision was made if the infrasternal angle was within normal limits (≥70°). Alternatively, if the infrasternal angle was less than 70°, a longitudinal incision was made. The xiphoid process was then resected to provide a widened operative view. In these cases, the sternum was not elevated. Blunt finger dissection created a retrosternal tunnel between the incision and the thoracic cavity and a wound protector was placed to further optimize the view. Any obstructing anterior mediastinal adipose tissue was removed. A 10 mm 30 o angle thoracoscope (Karl Storz, Tuttlingen, Germany) was used in each case (Figure 1). The right pleural cavity was opened initially, with the left lung being selectively ventilated. Electrocautery dissection of pericardial and epiphrenic fat pads was performed and then the right lobe of the thymus was identified and dissected from the pericardium and ascending aorta. Care was taken to visualize fully the innominate vein and superior vena cava junction prior to dissection of the thymic horn from the underlying innominate vein. The thymic ...