“…Our finding is in keeping with findings of Agner and Gallis, who observed that tuberculosis and malignant effusion were more likely to cause large pericardial effusion, effusion causing haemodynamic compromise compared to those secondary to idiopathic pericarditis [ 11 ]. Other studies done in regions with high endemicity for TB also revealed TB as the most common cause of pericardial effusion [ 12 , 13 ]. All our patients suspected to have TB pericardial effusion received an initial 4-drug therapy for 2 months (isoniazid, rifampicin, pyrazinamide, and ethambutol) followed by isoniazid and rifampicin for the remaining 4 months.…”