Success of a Targeted Tuberculosis Testing and Treatment Program in a Foreign-Born Population, 2000-2004

Mooney, Lewis R.; Oxtoby, Margaret J.; Grabau, John C.; Rodriguez, Edwin M.

doi:10.1378/chest.130.4_meetingabstracts.95s-a

Cited by 1 publication

(4 citation statements)

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“…Five studies conducted recruitment at other venue types such as community health centers, social fairs, churches, and community centers. [ 16 , 25 – 27 , 30 ]. For example, Wieland 2011 [ 30 ] contacted FBP through an adult education center in Rochester, Minnesota, catering to FBP representing 70 countries.…”

Section: Resultsmentioning

confidence: 99%

“…Most commonly reported recruitment and retention strategies included provision of easily accessible testing sites (14 studies) [ 16 , 25 , 27 – 38 ]; use of multilingual staff or interpreters (11 studies) [ 16 , 25 – 29 , 33 – 34 , 36 – 38 ]; combining the recruitment and testing steps (10 studies) [ 16 , 25 – 27 , 29 , 34 – 38 ]; onsite evaluation of participants testing positive for TB infection (six studies) [ 27 , 29 , 31 , 32 , 35 , 37 ]; and advertising and marketing (five studies) [ 25 , 27 , 33 , 35 , 38 ]. Many studies used multiple strategies to enhance recruitment, for example, combining advertising or marketing with residence based recruitment.…”

Section: Resultsmentioning

confidence: 99%

“…All but one study used TST exclusively for screening. Mooney 2006 [ 27 ] used a combination of TST and IGRA.…”

Section: Resultsmentioning

confidence: 99%

“…Hundreds of thousands of persons from high-burden Latin American and Caribbean countries enter the United States each year, many of whom are not authorized to be in the country [ 39 ]. There are millions of persons born in Asia or Africa currently residing in the United States who are potentially at elevated TB risk [ 40 ], though we found few publications that reported data on these populations [ 26 , 27 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

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Yield of community-based tuberculosis targeted testing and treatment in foreign-born populations in the United States: A systematic review

et al. 2017

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ObjectiveTo synthesize outputs and outcomes of community-based tuberculosis targeted testing and treatment (TTT) programs in foreign-born populations (FBP) in the United States (US).MethodsWe systematically searched five bibliographic databases and other key resources. Two reviewers independently applied eligibility criteria to screen citations and extracted data from included studies. We excluded studies that contained <50% FBP participants or that examined steps only after diagnosis of latent TB infection (LTBI). We stratified studies as majority FBP (50–90%) and predominantly FBP (>90%). We used random-effects meta-analytic models to calculate pooled proportions and 95% confidence intervals (CI) for community-based TTT cascade steps (e.g., recruited, tested and treated), and used them to create two hypothetical cascades for 100 individuals.ResultsFifteen studies conducted in 10 US states met inclusion criteria. Studies were heterogeneous in recruitment strategies and mostly recruited participants born in Latin America. Of 100 hypothetical participants (predominantly FBP) reached by community-based TTT, 40.4 (95% CI 28.6 to 50.1) would have valid test results, 15.7 (95% CI 9.9 to 21.8) would test positive, and 3.6 (95% CI 1.4 to 6.0) would complete LTBI treatment. Likewise, of 100 hypothetical participants (majority FBP) reached, 77.9 (95% CI 54.0 to 92.1) would have valid test results, 26.5 (95% CI 18.0 to 33.5) would test positive, and 5.4 (95% CI 2.1 to 9.0) would complete LTBI treatment. Of those with valid test results, pooled proportions of LTBI test positive for predominantly FBP and majority FBP were 38.9% (95% CI 28.6 to 49.8) and 34.3% (95% CI 29.3 to 39.5), respectively.ConclusionsWe observed high attrition throughout the care cascade in FBP participating in LTBI community-based TTT studies. Few studies included cascade steps prior to LTBI diagnosis, limiting our review findings. Moreover, Asia-born populations in the US are substantially underrepresented in the FBP community-based TTT literature.

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