Success Predictors of Endoscopic Sleeve Gastroplasty

Matteo, Maria Valeria; Bove, Vincenzo; Ciasca, Gabriele; Carlino, Giorgio; Di Santo, Riccardo; Vinti, Laila; Polidori, Giulia; Pontecorvi, Valerio; Papi, Massimiliano; Spada, Cristiano; Boškoski, Ivo

doi:10.1007/s11695-024-07109-4

Cited by 3 publications

(1 citation statement)

References 30 publications

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“…Males showed higher TBWL compared to females. A possible explanation for the better maintenance of weight loss among younger patients can be due to their ability to change behavioral habits and maintain diet [33]. If excluding behavioral elements between the genders, a possible reason for this difference can be attributed to the difference between body fat and muscle mass between the genders.…”

Section: Discussionmentioning

confidence: 99%

Pre-Procedural Predictors of Successful Endoscopic Sleeve Gastroplasty: A Retrospective Study

Charach,

Peleg,

Abuhasira

et al. 2024

Gastroenterology Insights

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Objective: Obesity is a major risk factor for the morbidity and mortality of cardiovascular disease and predicts the development of hypertension, diabetes mellitus and other various diseases. Methods: A retrospective study evaluated predictors for higher total body weight loss following endoscopic sleeve gastroplasty (ESG). Adults (>18 years old) with BMI > 30 kg/m2 who underwent ESG from January 2019 to July 2022 were included. Patients under the age of 18 were excluded from the study. Results: This retrospective cohort included 76 patients, of whom 62 women (81.6%) and 14 were men (18.4%) with a mean age of 46.3 ± 10.4. The mean BMI baseline was 36.6 ± 4.21. Out of the included patients, 10% were lost to follow-up at 1 month, 33% at 3 months, 50% after 6 months, and only 30% met 12 months follow-up. During the follow-up period, no mortality was documented. Three major adverse events (3.9%) were documented (one mediastinal abscess, one lower gastrointestinal bleeding and one pulmonary embolism), all of them in female patients. Among the demographic clinical and laboratory data examined, smoking (N = 6, p < 0.001) was associated with successful ESG, which was determined as total body weight loss (TBWL) above 15%. The rest of the variables examined were not shown to be statistically significant to sleeve success. Overall, 65 of the 76 patients which were studied in this research had more than 5% TBWL, 42 patients had more than 10% TBWL, 21 patients had more than 15% TBWL and 7 patients lost more than 20% of their weight during 1 year of follow-up. Maximal TBWL was achieved 3 months following the procedure. During the first month following ESG, the average weight lost was 8.6% (N = 69); at 3 months, it was 12.3% (N = 48); at 6 months, it was 11.3% (N = 33); and at 12 months, it was 9.8% (N = 13). Smoking was associated with higher weight loss. Conclusions: The current study showed a positive correlation between ESG weight loss above 15% and smoking. Older patients (>50) gained weight earlier, within 3 months, and by 1 year of follow-up almost returned back to their original weight. Females sustained weight loss over 1 year of follow-up compared to males. Patients with lower BMI continued losing weight during the follow-up period (12 months). This study tries to summarize pre-procedural prediction of ESG success.

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Section: Discussionmentioning

confidence: 99%

Pre-Procedural Predictors of Successful Endoscopic Sleeve Gastroplasty: A Retrospective Study

Charach,

Peleg,

Abuhasira

et al. 2024

Gastroenterology Insights

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Exploring novel circulating biomarkers for liver cancer through extracellular vesicle characterization with infrared spectroscopy and plasmonics

Di Santo,

Verdelli,

Niccolini

et al. 2024

Analytica Chimica Acta

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Assessing the predictive value of the suppressed 1 mg overnight dexamethasone suppression test in success of bariatric surgery

Şirikçi,

Kiraç,

Findikli

et al. 2024

Medicine

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Bariatric surgery has been proven to be a successful intervention for managing obesity. There are numerous studies in the literature aiming to predict the factors influencing the success of bariatric surgery. Our study aims to determine whether preoperative 1 mg overnight dexamethasone suppression test (1 mg-DST) serum cortisol levels can serve as predictors of the effectiveness of bariatric surgery in severe obese patients without Cushing syndrome. A total of 98 patients who underwent bariatric surgery were included in the study. The preoperative 1 mg-DST levels, insulin levels, thyroid function tests, and lipid profiles of the patients were recorded. The patients’ preoperative, postoperative 3rd, and 6th month weights were recorded and the percent total weight loss (%TWL) is calculated. Patients were categorized into 2 groups based on their TWL at 6 months. The 1 mg-DST results were significantly lower in the high-TWL-6 group (0.93 ± 0.37 μg/dL) compared to the low-TWL-6 group (1.09 ± 0.36 μg/dL, P = .040). Similarly, Homeostatic Model Assessment for Insulin Resistance values were lower in the high-TWL-6 group (5.63 ± 2.21) compared to the low-TWL-6 group (6.63 ± 2.55, P = .047). The optimal cutoff value found for 1 mg-DST level was 0.97 µg/dL, providing 50% sensitivity and 70% specificity. This study is the first to examine the predictive role of suppressed 1 mg-DST levels on postoperative weight loss in nondiabetic patients. The most prominent result of this study was that we observed a negative correlation between 1 mg-DST levels and %TWL.

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Success Predictors of Endoscopic Sleeve Gastroplasty

Cited by 3 publications

References 30 publications

Pre-Procedural Predictors of Successful Endoscopic Sleeve Gastroplasty: A Retrospective Study

Pre-Procedural Predictors of Successful Endoscopic Sleeve Gastroplasty: A Retrospective Study

Exploring novel circulating biomarkers for liver cancer through extracellular vesicle characterization with infrared spectroscopy and plasmonics

Assessing the predictive value of the suppressed 1 mg overnight dexamethasone suppression test in success of bariatric surgery

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