Successful detection of a minute tonsillar cancer lesion on transoral examination with narrow band imaging: A report of 2 cases

Ebisumoto, Koji; Okami, Kenji; Sakai, Akihiro; Sugimoto, Ryousuke; Iida, Masahiro

doi:10.1002/hed.24377

Cited by 15 publications

(12 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They refined the staging system into three recursive partitioning analysis (RPA) groups: RPA-I (T1-T3, N0-2b), RPA-II (T1-T3, N2c), and RPA-III (T4 or N3); this is a more accurate prognosis prediction system. [56]. Tumor was almost covered by normal mucosa (arrowheads).…”

Section: Clinical Staging For Opcmentioning

confidence: 97%

“…Transoral endoscopic examination with narrow-band imaging is thought to be effective to detect a small lesion (Fig. 2b) [56].Conversely, classical HPV-unrelated OPC arises from the surface area of the oropharynx, which is caused by tobacco smoking and alcohol exposure, and may therefore be more easily observed or diagnosed.…”

Section: Clinical Features Of Hpc-related Opsccmentioning

confidence: 98%

“…1). In such cases, the primary diagnosis would be cervical lymph node metastasis from carcinoma of unknown primary (CUP) [54][55][56]. The oropharynx should be thoroughly inspected to investigate the origin of CUP [53,[56][57][58].…”

Section: Clinical Features Of Hpc-related Opsccmentioning

confidence: 99%

“…Characteristic findings of HPV-related oropharyngeal squamous cell carcinoma (OPSCC)[56]. a Transoral video-endoscopic examination with normal white light reveals only the swelling of the left tonsil (arrow).…”

mentioning

confidence: 99%

See 3 more Smart Citations

Clinical features and treatment strategy for HPV-related oropharyngeal cancer

Okami

2016

Int J Clin Oncol

Self Cite

View full text Add to dashboard Cite

Among head and neck squamous cell carcinoma (HNSCC), the incidence of oropharyngeal SCC (OPSCC) is increasing in contrast to carcinoma with origin in other subsites. Human papillomavirus (HPV) is now recognized as a significant risk factor of the carcinogenesis of OPSCC. The HPV-related OPSCC patients tend to be relatively young, less exposed to tobacco and alcohol, and have a relatively high socioeconomic status and education level, which is distinct from HPV-unrelated classical OPSCC. The neck metastases tend to be aggressive and cystic. The better response to treatment resulting in improved prognosis of HPV-related OPSCC led to reconsidering the clinical staging and treatment approaches. Clinical trials of treatment deintensification to reduce the acute and late toxicity without compromising efficacy have been conducted. This review of HPV-related OPSCC focuses on current and generally accepted facts regarding the biology, epidemiology, and therapeutic strategy of this new disease entity.

show abstract

Section: Clinical Staging For Opcmentioning

confidence: 97%

Section: Clinical Features Of Hpc-related Opsccmentioning

confidence: 98%

Section: Clinical Features Of Hpc-related Opsccmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Clinical features and treatment strategy for HPV-related oropharyngeal cancer

Okami

2016

Int J Clin Oncol

Self Cite

View full text Add to dashboard Cite

show abstract

“…Ebisumoto et al [56] have reported their successful experience to detect minute p16-positive tonsillar cancer lesions on transoral examination with narrow band imaging (NBI). This imaging technique works by filtering white light into specific light wavelengths that are absorbed by haemoglobin and consequently enhances the visibility of the mucosal superficial vasculature [57].…”

Section: Identification Of Lesions In Individuals With a Positive Scrmentioning

confidence: 99%

Primary, secondary and tertiary prevention of human papillomavirus-driven head and neck cancers

Mirghani

Jung

Fakhry

2017

European Journal of Cancer

View full text Add to dashboard Cite

Narrow band imaging in head and neck unknown primary carcinoma: A systematic review and meta‐analysis

et al. 2019

View full text Add to dashboard Cite

Objective To estimate the diagnostic performance of Narrow Band Imaging (NBI) in patients with cervical metastasis from head and neck squamous cell carcinoma of unknown primary (SCCUP) origin. Methods PubMed, Embase, and Scopus databases were systematically scrutinized up to July 1, 2019, looking for studies that encompassed the NBI in the SCCUP diagnostic work up. The main inclusion criteria for eligible articles for the meta‐analysis were non‐evidence of primary tumor after physical examination and conventional cross‐section imaging before NBI assessment and the availability of complete data on the diagnostic accuracy of NBI. A set of random‐effects model meta‐analyses was then performed following the Meta‐analysis of Observational Studies in Epidemiology (MOOSE) guidelines. Results Five studies, conducted between January 2003 and September 2016, comprising 169 patients imaged with NBI, were included in the meta‐analysis. The pooled sensitivity and specificity of NBI in patients with head and neck SCCUP was 0.83 (99% CI, 0.54–0.95) and 0.88 (99% CI, 0.55–0.97), respectively. The positive and negative likelihood ratios were 6.38 (99% CI, 1.6–25.44) and 0.06 (99% CI, 0.005–0.86). The pooled diagnostic odds ratio (DOR) was 82.15 (99% CI, 7.06–955). The overall detection rate of NBI was 0.35 (99% CI, 0.18–0.53), which allowed localization the primary tumor in 61 out of 169 patients, otherwise not detected by the usual diagnostic work‐up. Conclusions Current available evidence suggests that NBI has a considerable diagnostic accuracy in patients affected by head and neck SCCUP. Laryngoscope, 130:1692–1700, 2020

show abstract

Successful detection of a minute tonsillar cancer lesion on transoral examination with narrow band imaging: A report of 2 cases

Cited by 15 publications

References 11 publications

Clinical features and treatment strategy for HPV-related oropharyngeal cancer

Clinical features and treatment strategy for HPV-related oropharyngeal cancer

Primary, secondary and tertiary prevention of human papillomavirus-driven head and neck cancers

Narrow band imaging in head and neck unknown primary carcinoma: A systematic review and meta‐analysis

Contact Info

Product

Resources

About