Successful en bloc transplantation of a horseshoe kidney without division of the isthmus: first case reported in South Africa

Zarrabi, Amir; Wessels, S; Vlok, Louis; Merwe, Anita van der

doi:10.17159/2078-5151/2017/v56n1a2174

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…Electronic databases were searched for case reports of transplantation of the horseshoe kidneys from 1975 to April 2022. There were 131 pairs of horseshoe kidneys, which were procured worldwide [44][45][46][47][48][49]. Fifty-three pairs of horseshoe kidneys were transplanted en bloc to a single recipient, and 78 pairs were divided at the isthmus with their blood supply separated and transplanted as single units to 131 recipients.…”

Section: Methodsmentioning

confidence: 99%

Transplantation of the Horseshoe Kidneys: A Model for Dual Adult Kidney Transplantation

Nghiem

2022

Uro

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Background: The shortage of organs has called for the use of two marginal adult kidneys (MAKs) with a low nephron mass as dual adult kidneys transplanted to a single recipient. The operative techniques of the transplantation of these kidneys are still debated. Since the horseshoe kidneys have been transplanted as early as 1975, it is theorized that the technique of the en bloc transplantation of the horseshoe kidney may be applied to the MAKs. Material and Methods: The world literature search during the period 1975–2021 on the use of deceased-donor horseshoe kidneys was reviewed. The selection of the donors, the anatomy of the kidneys, the principles of organ recovery, the transplantation procedure, and the results were discussed. Finally, this technique of en bloc transplantation was applied successfully to seven pairs of MAKs and is described herein. The dual adult kidneys were simultaneously vascularized by the donor aorta and vena cava, which were anastomosed, respectively, to the recipient iliac artery and vein. Results: A total of 131 case reports of deceased horseshoe kidney donors were reviewed, of which 53 en bloc kidneys were transplanted successfully to a single recipient, and the remaining 78 were divided and transplanted as single units to 131 recipients. Twenty-five single kidneys were discarded. At the time of publication, all horseshoe kidneys had a good renal function. In the series of seven pairs of MAKs transplanted en bloc, the operative time was 3 h. There were no primary nonfunctions, no vascular thromboses, no urinary leakages, and no wound infections. Only two patients required temporary dialysis despite an average of 28.4 h of cold ischemia time. No hydronephrosis and lymphocele was experienced. Both patient and graft survival were 100%. At the time of follow-up at 36 months, serum creatinine levels averaged 1.8 mg/dL (range 1.4–1.9). Conclusions: This technique of en bloc renal transplantation using the donor aorta and vena cava for revascularization can be applied to both the horseshoe kidneys and the MAK, and improve organ utilization.

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Section: Methodsmentioning

confidence: 99%

Transplantation of the Horseshoe Kidneys: A Model for Dual Adult Kidney Transplantation

Nghiem

2022

Uro

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“…[23] [24] It has allowed the treatment of males with extremely low counts, low motility, or even those who require surgical sperm extraction to obtain gametes. [25] [26] [27] Because of a reduction in failed fertilization, ICSI has evolved into the method of choice for insemination in the ART laboratory over the last thirty years. [23] [24] [28] [29] [30] [31] However, while ISCI may be seen as an almost universal means for oocyte insemination, it has limitations.…”

Section: Introductionmentioning

confidence: 99%

A Simple One-Step System Enhances the Availability of High-Quality Sperm for Assisted Reproductive Procedures

Prien,

Moseley,

Singh-Sharma

et al. 2023

OJOG

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Over the last forty years, in vitro fertilization, which has expanded to assisted reproductive technologies (ART), has gone from an experimental procedure to the mainstay of infertility treatment. A technique that once made news with each birth is now responsible for 2% -3% of the babies born in several nations of the world. This has happened due to significant advances in hormone therapies, culture techniques, and the specialization of equipment designed to support oocytes and embryos. However, for all the advances made to support female fertility, little has changed in male treatment since the advent of intracytoplasmic sperm injection in the early 1990's. Recently, a number of authors have documented problems with sperm preparation techniques. Some report DNA damage, others membrane and organelle issues, all of which potentially hamper fertilization rates and possibly take-home baby rates. Further, as the clinical workload of ART has increased and staffing shortages have become critical, all labs are looking for simpler, more efficient ways to perform job functions. This study describes a simple, one-step method for preparing semen samples for ART. This new technique minimizes excessive manipulation of the sample compared to current standards and is less likely to cause cell damage. Preliminary results suggest a significant enhancement in recovered sample motility and an optimal sample for ART procedures with minimal sample manipulation.

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Successful en bloc transplantation of a horseshoe kidney without division of the isthmus: first case reported in South Africa

Cited by 2 publications

References 7 publications

Transplantation of the Horseshoe Kidneys: A Model for Dual Adult Kidney Transplantation

Transplantation of the Horseshoe Kidneys: A Model for Dual Adult Kidney Transplantation

A Simple One-Step System Enhances the Availability of High-Quality Sperm for Assisted Reproductive Procedures

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