Successful First-in-Man Concomitant Transapical Transcatheter Aortic and Mitral Valve Replacements for Severe Native Aortic and Mitral Valve Stenosis Using the Edwards Certitude Delivery System

Abstract

Transcatheter aortic valve replacement (TAVR) has become the treatment of choice for high or intermediate risk patients with symptomatic severe aortic stenosis. Transcatheter mitral valve replacement (TMVR) for native mitral stenosis is still under investigation in clinical trials. Results from a global registry, however, show that TMVR in patients with severe mitral annulus calcification is feasible but associated with significant adverse events. Simultaneous TAVR and TMVR on native valves has only been reported twice. Here, we report the first case of simultaneous TAVR and TMVR for native aortic and mitral stenosis using the Edwards Certitude transapical delivery system.