Successful <i>in vitro</i> fertilization pregnancy following magnetic resonance‐guided focused ultrasound surgery for uterine fibroids

Zaher, Summia; Lyons, Deirdre; Regan, Lesley

doi:10.1111/j.1447-0756.2010.01344.x

Cited by 23 publications

(13 citation statements)

References 12 publications

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“…A case report from the United Kingdom [44] described the first successful case of in-vitro fertilization (IVF) after MRgFUS. A 45-year-old underwent MRgFUS for a single anterior intramural myoma with a NPV ratio of 90%.…”

Section: Pregnancy Following Magnetic-resonance-guided Focused Ultrasmentioning

confidence: 99%

“…Furthermore, women who have successful MRgFUS are generally older, and younger women have a higher incidence of hyperintense fibroids, which increase treatment difficulty [25]. Although there are single reports of intrauterine insemination [45] or IVF [44] after MRgFUS, data remain limited and the ideal timing of IVF after MRgFUS remains unknown.…”

Section: Magnetic-resonance-guided Focused Ultrasound Surgery Limitatmentioning

confidence: 99%

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Reproductive impact of MRI-guided focused ultrasound surgery for fibroids

Clark¹,

Segars

2014

Current Opinion in Obstetrics &Amp; Gynecology

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Purpose of review Magnetic-resonance-guided focused ultrasound surgery (MRgFUS) is a minimally invasive technique for the treatment of uterine fibroids. The purpose of this review is to highlight the impact of MRgFUS on fertility and reproductive outcomes. Recent findings The role of MRgFUS in the treatment of fibroids has been evolving since its introduction in 2004. Several new devices and techniques including location-specific treatment, volumetric therapy, and vessel-targeted therapy have been introduced over the last few years. Several case series report uncomplicated pregnancy following MRgFUS; however, results of the ongoing studies will further elucidate the utility of MRgFUS in patients planning future fertility. A systematic review of the literature was completed and studies that reported quality of life at baseline and after 6 months were included in a meta-analysis. Summary MRgFUS represents a minimally invasive treatment for uterine fibroids that is able to improve the quality of life and fibroid size with durability. It is possible that MRgFUS could be the treatment of choice for patients desiring future fertility; however, further investigation is needed.

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Section: Pregnancy Following Magnetic-resonance-guided Focused Ultrasmentioning

confidence: 99%

Section: Magnetic-resonance-guided Focused Ultrasound Surgery Limitatmentioning

confidence: 99%

Reproductive impact of MRI-guided focused ultrasound surgery for fibroids

Clark¹,

Segars

2014

Current Opinion in Obstetrics &Amp; Gynecology

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“…Unlike the earlier methods of myoma coagulation that involved multiple ablations of fibroids without imaging guidance, today's volumetric, image-guided ablation permits the operator to ablate a fibroid with a single ablation in most cases, and often in a fashion that confines the ablation to the myoma and spares the surrounding myometrium and endometrium. For additional support, there have been more than 50 reported cases of pregnancy after MRI-guided focused ultrasound, another form of hyperthermic ablation, with generally good outcomes and no reports of uterine rupture [52–55]. …”

Section: Clinical Studies Of Volumetric Radiofrequency Ablation Ofmentioning

confidence: 99%

Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids

Jones

O’Donovan

Toub

2012

Obstetrics and Gynecology International

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The use of thermal energy-based systems to treat uterine fibroids has resulted in a plethora of devices that are less invasive and potentially as effective in reducing symptoms as traditional options such as myomectomy. Most thermal ablation devices involve hyperthermia (heating of tissue), which entails the conversion of an external electromagnetic or ultrasound waves into intracellular mechanical energy, generating heat. What has emerged from two decades of peer-reviewed research is the concept that hyperthermic fibroid ablation, regardless of the thermal energy source, can create large areas of necrosis within fibroids resulting in reductions in fibroid volume, associated symptoms and the need for reintervention. When a greater percentage of a fibroid's volume is ablated, symptomatic relief is more pronounced, quality of life increases, and it is more likely that such improvements will be durable. We review radiofrequency ablation (RFA), one modality of hyperthermic fibroid ablation.

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“…HIFU technique is reported to promote the relief of symptoms due to adenomyosis 1112. Also, studies have been going on about the impaired implantation and habitual miscarriage in subfertility cases due to adenomyosis 1314…”

Section: Introductionmentioning

confidence: 99%

Clinical Consideration of Treatment to Ablate Uterine Fibroids with Magnetic Resonance Imaging-guided High Intensity Focused Ultrasound (MRgFUS): Sonalleve

Jeong¹,

Hong²,

Kim³

et al. 2016

J Menopausal Med

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ObjectivesMagnetic resonance imaging (MRI)-guided high intensity focused ultrasound surgery (MRgFUS) is a newly emerging non-invasive technique for the treatment of uterine fibroids. The purpose of this study is to review the clinical impact of MRgFUS.MethodsThis study examined 157 patients. The high intensity focused ultrasound (HIFU) utilized in this study was Philips Achieva 1.5 Tesla MR (Philips Healthcare, Best, the Netherlands) and Sonalleve HIFU system. The patients were followed in post-operative Month 1, Month 3, and Month 6 to investigate any change. Then, these were further classified according to the use of uterine stimulant (oxytocin) in parallel, Funaki Type of uterine fibroid, HIFU intensity, and non-perfused volume (NPV) ratio.ResultsWhen the uterine stimulant was utilized, the HIFU intensity was measured at significantly lower levels, compared with the group not using uterine stimulant, and treatment duration was significantly. The NPV ratio was found significantly higher in the group using uterine stimulant. Concerning the correlation between Funaki Type of uterine fibroid and average sonication power, it was found that the closer to Type I, the lower the sonication power, the shorter the treatment duration, and the higher the NPV ratio significantly.ConclusionsIn this study, it was found that the lower the Funaki Types of uterine fibroids, and the higher the NPV ratio immediately after the operation, the larger the uterine fibroid volume decrease and SSS change were. Also, if uterine stimulant was used in parallel in treatment, treatment duration and HIFU intensity could become shorter and lower.

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Successful in vitro fertilization pregnancy following magnetic resonance‐guided focused ultrasound surgery for uterine fibroids

Cited by 23 publications

References 12 publications

Reproductive impact of MRI-guided focused ultrasound surgery for fibroids

Reproductive impact of MRI-guided focused ultrasound surgery for fibroids

Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids

Clinical Consideration of Treatment to Ablate Uterine Fibroids with Magnetic Resonance Imaging-guided High Intensity Focused Ultrasound (MRgFUS): Sonalleve

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