Successful Management of a Recurrent Primary Malignant Fibrous Histiocytoma of the Lung: Report of a Case

Jeon, Yunho; Park, Ki Sung

doi:10.5090/kjtcs.2012.45.5.345

Cited by 5 publications

(4 citation statements)

References 5 publications

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“…In order to find a better treatment and improve the survival rate, we performed next-generation DNA sequencing (NGS) of MFH tissue from a 61-year-old male with primary pulmonary MFH. In addition, we summarized the clinical features and prognosis of this rare pulmonary malignant tumor based on the published literature (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23).…”

Section: Introductionmentioning

confidence: 99%

Primary pulmonary malignant fibrous histiocytoma: case report and literature review

Li¹,

Liu²,

Shi³

et al. 2017

J. Thorac. Dis.

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Malignant fibrous histiocytoma (MFH) is an aggressive soft tissue sarcoma known to occur in various organs. Primary MFH arising in the lung is quite rare. Herein we report a case of a 61-year-old male with primary pulmonary MFH and explore the underlying molecular mechanisms by next-generation sequencing (NGS). Five gene mutations in TSC2, ARID1B, CDK8, KDM5C and CASP8 were detected, and the mTOR inhibitor might be an effective treatment for this patient. In addition, we reviewed the scientific literature of approximately 23 primary pulmonary MFH case reports since 1990 and summarized the clinical features and prognosis of this rare pulmonary malignant tumor.

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Section: Introductionmentioning

confidence: 99%

Primary pulmonary malignant fibrous histiocytoma: case report and literature review

Li¹,

Liu²,

Shi³

et al. 2017

J. Thorac. Dis.

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“…In general, chest CT scan is one of the most useful examinations to determine not only location of the tumor but also tumor spread and mediastinal lymph node involvement. As previously reported, FDG PET/CT scan showed significantly increased uptake in the primary pulmonary UPS . It is still unclear how frequent pulmonary UPS shows high level of uptake by FDG PET/CT.…”

Section: Discussionmentioning

confidence: 50%

Primary undifferentiated pleomorphic sarcoma (Malignant fibrous histiocytoma) of the lung: A case report

Miyashita

Ikeda

Hiraoka

2019

Clinical Case Reports

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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. AbstractPrimary UPS of the lung, so-called MFH, is a rare aggressive neoplasm and known to be a high risk of recurrence and metastasis. Surgical resection without residual tumor is the main option of treatment and the best chance for long-term survival. K E Y W O R D Slobectomy, lung, malignant fibrous histiocytoma, undifferentiated pleomorphic sarcoma

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“…Favorable factors for MFHs are: UICC/AJCC stage I and II, superficial location, myxoid type, and patient under 50 years of age. Under these conditions, the rational for radical en-block resection of the tumor is supported [ 6 - 10 ].…”

Section: Discussionmentioning

confidence: 99%

Combined pulmonary lobectomy for surgical treatment of a malignant fibrous histiocytoma of the chest wall: a case report

Liu

Chen

et al. 2014

Diagn Pathol

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BackgroundA malignant fibrous histiocytoma (MFH) rarely originates from the chest wall.Clinical findingsIn this case, we describe a 59-year-old Chinese woman who presented with an enormous mass originating from the left chest wall and involving the left upper pulmonary lobe.TherapyAfter a radical en-block resection of the entire chest mass with left upper pulmonary lobectomy, and the chest wall reconstruction, a histopathologic diagnosis of the giant cell MFH was rendered. She has done well postoperatively, showing no local recurrence or distal disease in an 8-month follow-up period.ConclusionAlthough a MFH originating from the chest wall is rare, it should be considered in the differential diagnosis of a chest wall tumor.Virtual slidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/8895569301129379

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Successful Management of a Recurrent Primary Malignant Fibrous Histiocytoma of the Lung: Report of a Case

Cited by 5 publications

References 5 publications

Primary pulmonary malignant fibrous histiocytoma: case report and literature review

Primary pulmonary malignant fibrous histiocytoma: case report and literature review

Primary undifferentiated pleomorphic sarcoma (Malignant fibrous histiocytoma) of the lung: A case report

Combined pulmonary lobectomy for surgical treatment of a malignant fibrous histiocytoma of the chest wall: a case report

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