Successful Management of a Renin-Secreting Tumor in Pregnancy: A Case Report

Abstract

Hypertension that develops during early pregnancy has several causes. However, there have been no reported cases of full-term delivery, particularly when it is caused by renin-secreting renal tumors. We present the case of a 28-year-old pregnant patient who delivered with a renin-secreting renal tumor and provide a literature search of similar cases. A patient with no history of hypertension was referred to our hospital for severe hypertension during early pregnancy and was admitted for antihypertensive and aspirin therapy. The renin level of the patient was abnormally high, and a renal tumor was detected in the right kidney. Robot-assisted partial nephrectomy was performed at 16 weeks of gestation, after which antihypertensive medication was discontinued because hypertension was not observed. The pregnancy progressed favorably, leading to an uncomplicated delivery of a healthy baby at 40 weeks of gestation. The successful treatment of our patient can be attributed to three key factors: early hospitalization for strict blood pressure control, aspirin administration, and prompt diagnosis and treatment. Medication and thorough investigation of secondary hypertension are crucial in pregnant women with hypertension.