2012
DOI: 10.1155/2012/530908
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Successful Management of Acute Catastrophic Juvenile Vaginal Bleeding in Glanzmann’s Thromboasthenia by Uterine Tamponade: A Case Report and Review of The Literature

Abstract: Glanzmann’s thromboasthenia (GT) is a rare platelet disorder, due to membrane defects involving glycoprotein GP IIb/IIIa complex. Symptoms appear in infancy with episodes of bruising, gingival bleeding, epistaxis, or at the time of menarche acute episode of uterine bleeding. Hormonal therapy and antifibrinolytic agents are first-line treatment. Platelet transfusion is given to control hemorrhage when medical treatment fails. However, repeated transfusions may result in development of platelet refractio… Show more

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Cited by 2 publications
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“…One hundred and thirty‐two articles were examined in full text, of which 69 were eventually included in this systematic review. These comprised 61 case reports and series and eight cohort studies . The exact number of women with HMB is uncertain due to incomplete reporting in one article .…”
Section: Resultsmentioning
confidence: 99%
“…One hundred and thirty‐two articles were examined in full text, of which 69 were eventually included in this systematic review. These comprised 61 case reports and series and eight cohort studies . The exact number of women with HMB is uncertain due to incomplete reporting in one article .…”
Section: Resultsmentioning
confidence: 99%
“…Surgical therapy for acute HMB is rarely indicated, however there are case reports where Foley catheters provided intra-uterine tamponade in girls with acute anovulatory peri-menarchal bleeding and underlying bleeding disorders. 49,50 Evidence of haemodynamic compromise?…”
Section: The Management Of Acute Heavy Menstrual Bleedingmentioning
confidence: 99%