Successful management of bee sting induced Aspergillus fumigatus endophthalmitis and scleritis

Dogra, Mohit; Narang, Subina; Sood, Sunandan; Gupta, Pratiksha

doi:10.4103/ijo.ijo_889_17

Cited by 6 publications

(2 citation statements)

References 6 publications

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“…Endothelial cell damage, inflammatory mediators, and the resulting abnormal blood coagulation are key factors affecting organ function, causing abnormal blood vessel tension and inhibiting myocardial pump function, ultimately leading to organ damage. 14 The first 24 h to 2 wk after a person is stung by a swarm of wasps is a critical period to prevent and treat MODS. Urine output and color changes must be recorded every hour for the first 48 h. The observation of a patient's appetite, abdominal pain, bloating, nausea, vomiting, stool color, and skin and mucous membrane color is necessary.…”

Section: Discussionmentioning

confidence: 99%

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Hybrid Blood Purification in the Treatment of Multiple Organ Dysfunction Syndrome Following a Wasp Attack

Liu

Zhan

Ran

et al. 2022

Wilderness & Environmental Medicine

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Severe wasp sting symptoms can progress rapidly, often causing multiple organ dysfunction syndrome (MODS) and, in some cases, even death. Early and comprehensive treatment is needed to avoid these outcomes. Here, we report the case of a patient with MODS due to severe wasp stings. The patient received conventional treatment combined with glucocorticoids, plasma exchange, hemoperfusion, and continuous renal replacement therapy and had a successful recovery. MODS is a serious potential complication of wasp stings. Early local wound treatment, antiallergy interventions, antishock therapy, fluid replacement, glucocorticoid administration, and blood purification treatments are required to treat MODS secondary to wasp stings. Our results suggest that a hybrid blood purification method involving plasma exchange combined with hemoperfusion and continuous renal replacement therapy is more clinically effective than the single blood purification method. Early use of high-dose glucocorticoids combined with a hybrid blood purification treatment method had a positive effect in managing our patient and may improve the prognosis of other patients with MODS.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Hybrid Blood Purification in the Treatment of Multiple Organ Dysfunction Syndrome Following a Wasp Attack

Liu

Zhan

Ran

et al. 2022

Wilderness & Environmental Medicine

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Bee sting presumed endophthalmitis: a devastating ocular outcome

2021

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Background To report a rare case of bee sting presumed endophthalmitis that resulted in a devastating ocular outcome. Case presentation A 43-year-old patient presented 24 h after bee sting ocular injury in his left eye. He had a mild inflammatory sign at presentation, and he underwent surgical exploration to rule out a scleral defect, which revealed a sealed defect. During his hospital course, he developed signs of endophthalmitis 48 h following trauma for which he received vitreous tap and intravitreal antibiotic. Microbial culture revealed gram-negative rods, Pseudomonas aeruginosa, and Aeromonas veronii. Condition escalated to reach the panophthalmitis stage and cellulitis like picture with visual acuity of no light perception. Visual evoked response (VER) demonstrated a flat response. Infection was controlled by evisceration of the globe at the end as salvage therapy against the spreading of infection Conclusions Bee sting ocular injury is an exceedingly rare type of ocular trauma. Concomitant infection can happen, and severity depends on the pathogen involved. It is crucial to have insight and start appropriate treatment based on to the patient presentation.

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<p>Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights</p>

Spadea¹,

Giannico²

2019

OPTH

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Fungal endophthalmitis is subsequent to endogenous or exogenous infection and represents an important complication of ocular surgery which may lead to significant visual loss and blindness. The prognosis is poor because of delayed diagnosis and limited availability of effective antifungal drugs with good ocular penetration. Furthermore, the critical issue in diagnosing fungal infection of the eye is microbiological identification of the etiologic agent in clinical samples. Aspergillus is among the most frequent isolated organisms in fungal endophthalmitis. Early diagnosis is essential to prevent severe complications and blindness. Treatments include local, systemic and surgical therapeutic strategies. The purpose of the present review is the analysis of the current procedures adopted to promptly diagnose and treat Aspergillus endophthalmitis.

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Successful management of bee sting induced Aspergillus fumigatus endophthalmitis and scleritis

Cited by 6 publications

References 6 publications

Hybrid Blood Purification in the Treatment of Multiple Organ Dysfunction Syndrome Following a Wasp Attack

Hybrid Blood Purification in the Treatment of Multiple Organ Dysfunction Syndrome Following a Wasp Attack

Bee sting presumed endophthalmitis: a devastating ocular outcome

<p>Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights</p>

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