Successful management of bilateral periorbital necrotising fasciitis with ocular involvement

Setiawati, Wida; Satari, Hinky Hindra Irawan; Irawati, Yunia; Susiyanti, Made

doi:10.1136/bcr-2017-223457

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…Necrotizing fasciitis can be serious, possibly leading to septicemia and death [11]. Treatment necessitates serial surgical debridement and broad-spectrum antibiotics, and some research has shown benefit to hyperbaric oxygen therapy [12,13]. A delay in surgical debridement is the highest risk factor for all-cause mortality in necrotizing fasciitis [10].…”

Section: Group Descriptionmentioning

confidence: 99%

Bilateral Ocular Necrotizing Fasciitis in an Immunosuppressed Patient on Prescription Eye Drops

Landeen

Mallory

Cervenka

2020

Cureus

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Preseptal cellulitis is an infection of ocular tissue that is often unilateral and caused by extension of sinonasal disease. In rare instances it can lead to life-threatening necrotizing fasciitis. We present here a unique case of bilateral preseptal cellulitis incited by local conjunctivitis caused by prescription eye drops. The patient was immunosuppressed, which allowed her local inflammation to progress to severe infection and, ultimately, to necrotizing fasciitis. This necessitated serial debridement by ophthalmology and otolaryngology teams and a prolonged course of intravenous antibiotics monitored by an infectious disease team. Despite these interventions, the patient's vision did not return to baseline and she had persistent cosmetic and functional deformity. This case is unique due to the inciting incident of new prescription eye drops, the patient's immunosuppressed state leading to severity of infection, and the severe bilateral disease burden.

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Section: Group Descriptionmentioning

confidence: 99%

Bilateral Ocular Necrotizing Fasciitis in an Immunosuppressed Patient on Prescription Eye Drops

Landeen

Mallory

Cervenka

2020

Cureus

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“…Necrotizing fasciitis (NF) is a life-threatening form of infection involving rapidly spreading inflammation and extensive necrosis of the skin, subcutaneous tissue, and superficial fascia with or without overlying cellulitis [1] . NF is a rare soft tissue infection and the incidence of NF in the world range from 0.30 to 15 cases per 100,000 people [2] .…”

Section: Introductionmentioning

confidence: 99%

Necrotizing fasciitis in Indonesian adult with diabetes mellitus: Two case and review article

Putri

Novida

2022

International Journal of Surgery Case Reports

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A systematic review of necrotising fasciitis in children from its first description in 1930 to 2018

Schröder¹,

Gerin

Firth

et al. 2019

BMC Infect Dis

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Background Necrotising fasciitis is a rapidly progressing soft-tissue infection with a low incidence that carries a relevant risk of morbidity and mortality. Although necrotising fasciitis is often fatal in adults, its case fatality rate seems to be lower in children. A highly variable clinical presentation makes the diagnosis challenging, which often results in misdiagnosis and time-delay to therapy. Methods We conducted a protocol-based systematic review to identify specific features of necrotising fasciitis in children aged one month to 17 years. We searched ’PubMed’, ’Web of Science’ and ’SCOPUS’ for relevant literature. Primary outcomes were incidence and case fatality rates in population-based studies, and skin symptoms on presentation. We also assessed signs of systemic illness, causative organisms, predisposing factors, and reconstructive procedures as secondary outcomes. Results We included five studies reporting incidence and case fatality rates, two case-control studies, and 298 cases from 195 reports. Incidence rates varied between 0.022 and 0.843 per 100,000 children per year with a case-fatality rate ranging from 0% to 14.3%. The most frequent skin symptoms were erythema (58.7%; 175/298) and swelling (48%; 143/298), whereas all other symptoms occurred in less than 50% of cases. The majority of cases had fever (76.7%; 188/245), but other signs of systemic illness were present in less than half of the cohort. Group-A streptococci accounted for 44.8% (132/298) followed by Gram-negative rods in 29.8% (88/295), while polymicrobial infections occurred in 17.3% (51/295). Extremities were affected in 45.6% (136/298), of which 73.5% (100/136) occurred in the lower extremities. Skin grafts were necessary in 51.6% (84/162) of the pooled cases, while flaps were seldom used (10.5%; 17/162). The vast majority of included reports originate from developed countries. Conclusions Clinical suspicion remains the key to diagnose necrotising fasciitis. A combination of swelling, pain, erythema, and a systemic inflammatory response syndrome might indicate necrotising fasciitis. Incidence and case-fatality rates in children are much smaller than in adults, although there seems to be a relevant risk of morbidity indicated by the high percentage of skin grafts. Systematic multi-institutional research efforts are necessary to improve early diagnosis on necrotising fasciits. Electronic supplementary material The online version of this article (10.1186/s12879-019-3941-3) contains supplementary material, which is available to authorized users.

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Successful management of bilateral periorbital necrotising fasciitis with ocular involvement

Cited by 4 publications

References 13 publications

Bilateral Ocular Necrotizing Fasciitis in an Immunosuppressed Patient on Prescription Eye Drops

Bilateral Ocular Necrotizing Fasciitis in an Immunosuppressed Patient on Prescription Eye Drops

Necrotizing fasciitis in Indonesian adult with diabetes mellitus: Two case and review article

A systematic review of necrotising fasciitis in children from its first description in 1930 to 2018

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