2021
DOI: 10.1136/bcr-2020-240613
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Successful management of small cell neuroendocrine carcinoma of the ureter with neoadjuvant chemotherapy and adjuvant chemoradiation: case report and literature review

Abstract: Neuroendocrine tumours (NETs) of the urinary tract are rare, and the urinary bladder is the the most common primary site. Primary ureteric NET is rarer with under 80 cases reported in the literature thus far. Most of these tumours are of the high-grade small cell neuroendocrine carcinoma subtype, which has a worse prognosis. Neoadjuvant chemotherapy has a proven role in the management of NET of the bladder as it downstages the tumour, which may add to significant recurrence-free survival and overall survival. … Show more

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Cited by 2 publications
(3 citation statements)
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“…5 There is currently no consensus on the management of primary small cell carcinoma of the ureter, and some case reports recommend cisplatin-based neoadjuvant chemotherapy followed by nephroureterectomy. [6][7][8] We reported a unique case of postoperative metastasis of small cell carcinoma of the ureter detected by 18 F-FDG PET/CT. The definitive diagnosis and aggressive surveillance are very important because of the poor prognosis.…”
Section: Figurementioning
confidence: 99%
See 1 more Smart Citation
“…5 There is currently no consensus on the management of primary small cell carcinoma of the ureter, and some case reports recommend cisplatin-based neoadjuvant chemotherapy followed by nephroureterectomy. [6][7][8] We reported a unique case of postoperative metastasis of small cell carcinoma of the ureter detected by 18 F-FDG PET/CT. The definitive diagnosis and aggressive surveillance are very important because of the poor prognosis.…”
Section: Figurementioning
confidence: 99%
“…4% and 23.8%, and pathological stage was the only significant prognostic factor for overall survival 5. There is currently no consensus on the management of primary small cell carcinoma of the ureter, and some case reports recommend cisplatin-based neoadjuvant chemotherapy followed by nephroureterectomy [6][7][8]. We reported a unique case of postoperative metastasis of small cell carcinoma of the ureter detected by 18 F-FDG PET/CT.…”
mentioning
confidence: 91%
“…Thus, surgery alone does not result in the complete cure of patients. Multimodal therapy, including radiotherapy and chemotherapy, becomes necessary (Farooq et al 2021). At present, postoperative radiotherapy remains controversial.…”
Section: Introductionmentioning
confidence: 99%