Successful pregnancy after thermal balloon endometrial ablation followed by in vitro fertilization and embryo transfer

Kužel, D; Bartosová, L; Řežábek, K; D, Tóth; Cindr, Josef; Mára, Michal

doi:10.1016/j.fertnstert.2009.09.061

Cited by 6 publications

(3 citation statements)

References 15 publications

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“…Interestingly, a small group of women had a sterilization reversal or in vitro fertilization procedure post‐ablation, which suggests an intention to become pregnant. Although uncommon, there have been reports of sterilization reversals and intended pregnancies following endometrial ablation 22‐24 . Similarly, findings of regret and request for tubal ligation reversal are more common among younger and nulliparous women, 25 leading to guidelines specifically discussing the issue of regret for women seeking permanent sterilization if under 30 years old 26 .…”

Section: Discussionmentioning

confidence: 99%

“…Although uncommon, there have been reports of sterilization reversals and intended pregnancies following endometrial ablation. [22][23][24] Similarly, findings of regret and request for tubal ligation reversal are more common among younger and nulliparous women, 25 leading to guidelines specifically discussing the issue of regret for women seeking permanent sterilization if under 30 years old. 26 These findings together highlight the importance of careful counseling and decision-making regarding treatment options for heavy menstrual bleeding, especially for treatments that are likely to have long-term effects on fertility.…”

Section: Discussionmentioning

confidence: 99%

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A study of pregnancy after endometrial ablation using linked population data

Ibiebele

Nippita

Baber

et al. 2020

Acta Obstet Gynecol Scand

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Introduction Endometrial ablation encapsulates a range of procedures undertaken to destroy the endometrial lining of the uterus as a treatment for heavy menstrual bleeding in women who no longer wish to bear children. Pregnancy following ablation, while unlikely, can occur and may carry higher rates of complications. The aim of this study was to identify factors associated with post‐endometrial ablation pregnancy and to describe pregnancy and birth outcomes for post‐endometrial ablation pregnancies. Material and methods This population‐based data linkage study included all female residents of New South Wales, Australia, aged 15‐50 years with a hospital admission between July 2001 to June 2014 who birthed between July 2001 and June 2015. Cox proportional hazard regression was used to estimate associations between women’s characteristics and post‐endometrial ablation pregnancy of at least 20 weeks’ gestation. Descriptive statistics were used to characterize pregnancy and birth outcomes. Results Of 18 559 women with an endometrial ablation, 575 (3.1%) had a post‐ablation pregnancy of at least 20 weeks’ gestation. Nulliparity (adjusted hazard ratio [aHR] 12.2, 95% confidence interval [CI] 9.1‐16.2), older age (35‐39 years: aHR 0.39, 95% CI 0.29‐0.51; 40‐44 years: aHR 0.06, 95% CI 0.04‐0.11), marital status (single: aHR 0.67, 95% CI 0.55‐0.83; widowed/divorced/separated: aHR 0.58, 95% CI 0.36‐0.94) and a diagnosis of heavy menstrual bleeding (aHR 0.09, 95% CI 0.07‐0.13) were associated with post‐ablation pregnancy. There were high rates of cesarean delivery (43%), preterm birth (13%), twin or higher order pregnancies (9%) and stillbirth (13.3/1000 births) among these post‐ablation pregnancies. Conclusions Nulliparity at the time of endometrial ablation is associated with increased risk of post‐ablation pregnancy, highlighting the importance of careful discussion and consideration of treatment options for heavy menstrual bleeding.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A study of pregnancy after endometrial ablation using linked population data

Ibiebele

Nippita

Baber

et al. 2020

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

show abstract

“…However, unlike hysterectomy, pregnancy after endometrial ablation is possible although it is not often (Kdous et al, 2008). Premenopausal women should have a post-operative contraception method, because serious complications such as spontaneous abortion, prematurity, uterine rupture, and placenta adhesion complications in the pregnancies after endometrial ablation have been reported (Laberge, 2008;Kuzel et al, 2010;Yin , 2010).…”

Section: Endometrial Resection and Ablationmentioning

confidence: 99%