Successful pregnancy and delivery in a woman with a single ventricle and eisenmenger syndrome

Successful pregnancy and delivery in patients with uncorrected single ventricle: Three new cases and literature review

“…In the current study, we conducted a literature research and review for the pregnancy in UVH patients since 2000. To our best knowledge, a total of 9 cases of pregnancy in UVH patients have been reported since 2000 [1,2,[9][10][11][12][13], the results are summarized in Table 1. Except for one case [12] that showed severe maternal symptoms and obvious fetal growth delay with oligohydramnios and received a termination of pregnancy at 27-week gestation, all of the other 8 cases had a good outcome for both mother and fetus.…”

“…These results encouraged us to further review the outcome for pregnancy in UVH patient without surgical correction in the literature, as summarized in Table 2. Surprisingly, all of the reported cases since 1963 show good outcomes [1,2,4,[10][11][12][13][14][15][16][17][18][19][20][21][22]. It was suggested that UVH is not an absolute contraindication to pregnancy.…”

“…Gas analyses showed normal results. Echocardiography revealed a complex malformation consisting of (1) single ventricle (left type) with double outlets with an ejection fraction (EF) of 58%, (2) severe regurgitation in pulmonic valves, (3) dextro-malpositions of aortic arch, and (4) moderate regurgitation in tricuspid and mitral valves, but with normal veno-atrial connection. The ECG showed a sinus rhythm with extreme right axis deviation ( Fig.1 and Fig.…”

“…The occurrence of univentricular heart (UVH, or single ventricle) is rare, accounting for only 0.5-1.5% among patients suffering from congenital heart disease (CHD) [1,2]. In such condition, single ventricular pumping chamber supplies both systemic and pulmonary circulations, in which oxygenated and deoxygenated blood are mixed.…”

Pregnancy outcome in women with an uncorrected single ventricle: A single-centre experience from South India

“…1 Univentricular heart or single ventricle accounts for 0.5-1.5% of women with congenital heart disease. 2,3 Survival to adulthood is rare in uncorrected cases, with very few achieving successful pregnancy outcome. [2][3][4][5][6][7][8][9][10][11][12][13] Systemic and pulmonary circulations originate from the single ventricle where mixing of saturated and desaturated blood occurs, leading to a varying degree of systemic arterial desaturation.…”