Successful pregnancy and delivery of two sets of monozygotic twins after intracytoplasmic sperm injection and embryo transfer: case report and literature review

Grgić, Ozren; Ivanišević, Marina; Đelmiš, Josip; Lučinger, Dražen; Krile, Lana

doi:10.1016/j.fertnstert.2009.04.011

Cited by 5 publications

(7 citation statements)

References 16 publications

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“…A division between the 3rd and 8th days is the most frequent mechanism leading to high-order multiple pregnancies with, at least, a monochorionic biamniotic or triamniotic pregnancy (1)(2)(3)(4). However, in our case, a very early division (before the third day of development), in addition in both embryos, would have to have occurred to give bichorionic diamniotic monozygotic twins and/or trichorionic triamniotic monozygotic triplets.…”

Section: Discussionmentioning

confidence: 57%

See 1 more Smart Citation

Quintuplets after a transfer of two embryos following in vitro fertilization: a proved superfecundation

Peigné¹,

Andrieux

Philippe

et al. 2011

Fertility and Sterility

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Section: Discussionmentioning

confidence: 57%

“…Limiting the number of embryos transferred is one of the precautions. However, even if the number of transferred embryos is reduced, high-order multiple pregnancies can be observed (1)(2)(3)(4)(5). When the mechanism is uncertain, DNA analysis may be helpful.…”

mentioning

confidence: 99%

Quintuplets after a transfer of two embryos following in vitro fertilization: a proved superfecundation

Peigné¹,

Andrieux

Philippe

et al. 2011

Fertility and Sterility

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“…Ultrasound antepartum surveillance is the mainstay for monitoring fetal wellbeing and is essential for early diagnosis; vaginal ultrasound reveals the number of gestational sacs with accuracy (Ayres & Johnson, 2005). Ultrasound assessment of fetal growth and amniotic fluid volume should be scheduled every two weeks including nonstress tests and biophysical profiles later into the pregnancy and Doppler velocimetry in case of complications such as hypertension or fetal hypotrophy (Gregic et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Variable Outcome in Quintuplets Pregnancy Based on Obstetric Care

et al. 2011

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The incidence of multiple pregnancies has increased dramatically over the last few years in developed countries, largely attributed to delayed childbearing and the increasing use of assisted reproduction technologies and ovulation inducing hormones. Relatively few countries have population-based statistics covering birth statistics. Of those that do, the numbers of quintuplet pregnancies rose sharply in the nineties while, at the same time, their delivery rates decreased greatly because of the use of fetal reduction. Fetal reduction is not possible or legal in some countries, Poland being one of them, and therefore obstetricians are faced with the challenges of quintuplet deliveries. Conservative treatment and management is difficult, and outcomes often vary greatly. Despite this, expert care provided at tertiary care centers can positively influence outcomes. The objective of this article is to present different care options and their consequences in two illustrative cases, as well as to establish a set of obstetric care and management goals that would allow prolongation of the gestation time. Quintuplet pregnancy is rare but poses relevant clinical problems to both the obstetrician and the neonatologist. It should be managed with close cooperation between all concerned. Due to the extreme and invariable risk of premature delivery associated with quintuplet pregnancies, we recommend early diagnosis, adequate prenatal care at one tertiary medical center, routine hospitalization and bed rest, repeated ante partum ultrasound surveillance with tests of fetal well-being, tocolytic therapy at first signs of the risk of premature labor, and specialized neonatology care after delivery.

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“…Many studies exist in literature, including case reports, for quadruplet/quintuplet pregnancies after single/double blastocyst transfer. Quadruplet pregnancies have been reported after the transfer of only one [46] or two embryos [47][48][49], with variable chorionicity. There are also case reports of quintuplets originated from one fertilized egg (the Dionne quintuplets) and two [50,51] or three blastocysts [52].…”

Section: Predisposing Factors For a High-order Pregnancymentioning

confidence: 99%

Quadruplets and Quintuplets

Fiorentzis¹,

Salta²,

Pargianas³

et al. 2019

Multiple Pregnancy - New Challenges

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A high-order pregnancy is always a challenge not only for the couple but also for the obstetrician, the pediatricians, the midwives, and the whole stuff of an obstetric clinic. The breakthroughs of infertility treatments have made more couples to postpone the birth of their children until they feel professionally and financially safe, many times after the age of 40. The advanced age of the mother puts extra pressure to the clinician for immediate success, leading to a rise of high-order pregnancies until the introduction of regulations and laws in many countries. The cost of a quadruplet and quintuplet pregnancy can be unbearable, not only financially but also psychologically. The management of such a pregnancy is also challenging since its beginning and to the end. Modern techniques and methods can also be difficult to be implemented on a quadruplet of quintuplet pregnancy because of the fear of losing four or five embryos at once. At the same time, the limited number of cases makes it almost impossible for studies to be made and guidelines to be established for most of the cases.

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Successful pregnancy and delivery of two sets of monozygotic twins after intracytoplasmic sperm injection and embryo transfer: case report and literature review

Cited by 5 publications

References 16 publications

Quintuplets after a transfer of two embryos following in vitro fertilization: a proved superfecundation

Quintuplets after a transfer of two embryos following in vitro fertilization: a proved superfecundation

Variable Outcome in Quintuplets Pregnancy Based on Obstetric Care

Quadruplets and Quintuplets

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