Successful pregnancy in a patient with a 46,XY karyotype

Selvaraj, Kamala; Ganesh, Vijaya; Selvaraj, Priya

doi:10.1016/s0015-0282(02)03242-9

Cited by 32 publications

(20 citation statements)

References 5 publications

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“…However, patients with gonadal dysgenesis should be counselled that they have a uterus and may successfully conceive with ovum donation, give birth and breastfeed. 10 The 14 women in this sample with gonadal dysgenesis were aged 16 -42, and such information is of relevance to all of them, especially as many of the age-related pregnancy risks to the fetus are determined by the age of the ovum donor and not the ovum recipient.…”

Section: Discussionmentioning

confidence: 98%

XY females: revisiting the diagnosis

Minto

Crouch

Conway

et al. 2005

BJOG

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Objectives To investigate the accuracy of assigned diagnosis in XY female intersex conditions.Design Cross sectional hospital case notes review.Setting Tertiary hospital multidisciplinary intersex clinic.Sample Forty-six adult intersex women with a complete or mosaic XY karyotype.Methods All clinical features and investigation results were reviewed and a diagnosis was assigned. This was compared to the original diagnosis assigned. Main outcome measures Data collected included presentation, all investigations, subsequent clinical course and all treatments (medical and surgical). These data were employed to assign an up-to-date intersex diagnosis, which was compared with the recorded diagnosis in the hospital case notes. Diagnoses were then rated according to level of accuracy. Results The 47.8% patients had an accurate diagnosis, 32.6% of diagnoses were inaccurate and currently under review, 13% had a wrong diagnosis and 6.5% remain with an unknown aetiology for their XY intersex condition. Conclusions Diagnostic accuracy is assumed to be high when evaluating published work on these conditions; however, this study shows 52.1% of patients have unknown, inaccurate or wrong diagnoses. Assigning the wrong diagnosis may be harmful, for example, if it leads to irreversible virilising changes or development of a gonadal malignancy, and for all cases excludes accurate condition management and genetic counselling for both the patient and their immediate family.

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Section: Discussionmentioning

confidence: 98%

XY females: revisiting the diagnosis

Minto

Crouch

Conway

et al. 2005

BJOG

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show abstract

“…6 Only Kan et al and Selvaraj et al reported failed induction while Siddique et al and Michala et al reported successful vaginal delivery in three cases. 4,9,11,15 The hypoplastic uterus responds well to hormonal therapy and it may have anatomical ability to permit normal dilatation and labor however more reports with vaginal delivery would be required to support that.…”

Section: Discussionmentioning

confidence: 99%

Successful pregnancy outcome in a case of Swyer Syndrome with hypertension and morbid obesity

Kalra¹,

Nadkarni²,

Singh³

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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“…Early diagnosis and treatment could help these patients have a normal sex life and carry a fetus in an immature uterus. There are a number of case reports of successful pregnancies in these patients with the help of artificial reproductive techniques (17)(18)(19).…”

Section: Discussionmentioning

confidence: 99%