Successful pregnancy outcomes following use of enoxaparin in recurrent pregnancy loss without apl antibodies-report of 2 cases

Abstract

Recurrent Pregnancy losses are defined as pregnancy losses up to 20 weeks of gestation age. Most causes are thrombophilias of which positive Antiphospholipid antibodies are the commoners, others being hereditary thrombophilias, uterine defects, infections, endocrine disorders like DM, thyroid disorders, hyperprolactinemia etc. Usually the treatment that is offered is empirical like progesterone, dydrogesterone, IV immune globulins, and intralipids and in thrombophilias due to positive APL antibodies Enoxaparin and low dose aspirins recommended but not as a routine.Here we report 2 cases of RPL where there was no APL anybody positivity but early Enoxaparin was started till 33 weeks and we got a positive result in the form of live fetus born at 37 plus weeks in both cases.