Successful repair of a popliteal aneurysm with saphenous vein graft in a patient with Marfan syndrome

Abstract

Marfan syndrome is an autosomal dominant disorder caused by mutations in the fibrillin 1 gene (FBN1). This leads to defective elasticity of connective tissue in the arterial wall. Aortic aneurysms and dissections are the most common vascular anomalies; the incidence of peripheral artery aneurysms is not well understood. Treatment options for infrainguinal disease are limited as endovascular interventions are generally contraindicated. The best conduit for arterial reconstruction is also unknown because there is concern that saphenous vein may become aneurysmal. Currently, there are few case reports regarding outcomes of infrainguinal arterial reconstructions, and follow-up has been very short term. We report a rare case of successful repair of a popliteal aneurysm using a saphenous vein graft in a patient with Marfan syndrome.

Rotura de aneurisma de artéria poplítea em paciente clinicamente diagnosticado com síndrome de Marfan

“…We found reports of aneurysmal dilatations in other segments of the aorta, in visceral branches, pulmonary arteries, and peripheral arteries in patient with MFS, but few reports relating the syndrome to PAAs. [7][8][9][17][18][19] Yetman et al 17 conducted a study with 140 MFS patients over the age of 18. CT or MRI images were acquired from the base of the skull to the bifurcation of the iliac arteries.…”

“…4,5 Development of PAAs in patients with Marfan Syndrome (MFS) is rare, and few cases have been reported. [7][8][9] Gaertner et al 10 identified one patient with a PAA among 15 MFS patients who underwent vascular examination using ultrasound.…”