Successful resuscitation from SARS‐CoV‐2 infection in a child after Rastelli operation

Enhancing understanding of SARS-CoV-2 infection among individuals with Down syndrome: An integrative review

“…Heart defects were recurrent in DS individuals with COVID-19, mainly in the pediatric age group. 20 – 24 , 26 – 29 , 35 , 36 , 40 – 45 Children with DS seem more likely to be exposed to severe COVID-19 than those without DS. 46 …”

“…Although the main clinical manifestations of COVID-19 infection in individuals with DS are similar to those in other individuals, i.e., respiratory distress, fever, cough, and muscle pain, 20 the literature suggests that individuals with DS may have a distinct initial clinical presentation of COVID-19, 22 , 26 , 38 , 39 , 43 , 49 , 50 showing atypical symptoms such as hemoptysis, vomiting, diarrhea, abdominal pain, and autoimmune manifestations. 22 , 26 , 38 , 43 , 49 Additionally, unusual symptoms such as arrhythmia can be caused by underlying pathologies and mask the presence of respiratory symptoms. 24 , 26 These unusual symptoms were not directly related to a more severe course of COVID-19.…”

“… 22 , 26 , 38 , 43 , 49 Additionally, unusual symptoms such as arrhythmia can be caused by underlying pathologies and mask the presence of respiratory symptoms. 24 , 26 These unusual symptoms were not directly related to a more severe course of COVID-19. Nonetheless, it can be associated with a delay in diagnosis and treatment, potentially resulting in worse outcomes.…”

“…Heart defects were recurrent in DS individuals with COVID-19, mainly in the pediatric age group. [20][21][22][23][24][26][27][28][29]35,36,[40][41][42][43][44][45] Children with DS seem more likely to be exposed to severe COVID-19 than those without DS. 46 Simpson et al 24 presented a case series of seven children, three infection.…”

“…24 The other cardiopathies mentioned were primarily septal defects that were associated with severe infection and prolonged hospitalization. 24,26,27,36,[40][41][42]44 Some studies stated whether the heart defect was surgically corrected, while others did not, making it difficult to conclude if surgical treatment of the heart disease changes the natural progression or outcome of the COVID-19 disease.…”