2010
DOI: 10.1111/j.1399-3046.2010.01413.x
|View full text |Cite
|
Sign up to set email alerts
|

Successful second bone marrow transplantation in Omenn’s syndrome after bone marrow aplasia: A case report

Abstract: Omenn's syndrome is a rare inherited variant of SCID. It is inevitably fatal, unless treated by bone marrow or stem cell transplantation. However, treatment-related complications and graft rejection are major obstacles to the success of transplantation. In this report, we describe an eight-month-old baby with Omenn's syndrome and disseminated BCGosis, who underwent allogenic BMT from his HLA-matched sister using anti-GVHD prophylaxis but without a conditioning regimen. Ten days after BMT, he developed acute GV… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2019
2019
2022
2022

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(2 citation statements)
references
References 16 publications
0
2
0
Order By: Relevance
“…Intermittent fever, generalized lymphadenopathies, hepatosplenomegaly, cough, bone involvement, weight loss and skin rash may develop later in the course of the disease [15,26]. Refractory cough due to recurrent lower respiratory infections is another presentation of the disease reported in several cases [28], without significant changes in chest radiography [4]. Osseous involvement is another finding in disseminated BCG infection [6].…”
Section: Discussionmentioning
confidence: 99%
“…Intermittent fever, generalized lymphadenopathies, hepatosplenomegaly, cough, bone involvement, weight loss and skin rash may develop later in the course of the disease [15,26]. Refractory cough due to recurrent lower respiratory infections is another presentation of the disease reported in several cases [28], without significant changes in chest radiography [4]. Osseous involvement is another finding in disseminated BCG infection [6].…”
Section: Discussionmentioning
confidence: 99%
“…Omenn syndrome (OS) is one of the form of severe combined immunodeficiency (SCID) with autoreactive manifestations. Due to immune dysregulation, patients with OS typically have erythroderma, hepatosplenomegaly, lymphadenopathy, recurrent infections, and alopecia 1,2 .…”
Section: Introductionmentioning
confidence: 99%