“…For macromolecules and protein and peptide structures there have also been a number of encouraging published studies including: calcitonin (salmon) [29], corticotrophin-releasing hormone [30], delta sleep-inducing peptide [31], dextran sulphate [32], inulin [33], insulin [34][35][36][37][38], gonadotropinreleasing hormone [39], growth hormone-releasing factor [40], leuprolide acetate [23,41,43], leutenising hormonereleasing hormone [44][45][46], neutral thyrotrophin-releasing hormone [47], oligonucleotides [48,49], parathyroid hormone [50,51] and vasopressin [52,53]. To date, however, clinical studies have been limited to smaller molecules such as lidocaine [54][55][56], dexamethasone [57], etofenamate [58], naproxen [59], metoclopramide plus hydrocortisone [60], cortisone [61], vincristine [62] and fentanyl [63].…”