Successful treatment of alopecia areata and alopecia totalis with diphencyprone

The therapeutic use of topical contact sensitizers in benign dermatoses

“…The results of two studies of the same patients 49,93 were combined in the table to show long‐term outcome data, and a study which used both DPCP and SADBE was included in the SADBE table only 150 . The remaining 15 studies are included in Table 4 49,62,63,68,69,72,88,90–94,103,151–153 …”

“…Of the remaining 37 studies using DPCP, SADBE or DNCB (Table 6), only two were randomized placebo‐controlled trials 150,165 . Half‐head studies were common, using half the patient's head as untreated control ( n = 14), 41,42,49,52,64,88,90,94,103,151–153,180,181 treating half with the irritant sodium lauryl sulphate ( n = 1) 163 or in one case treating initially only a single patch 164 . The remaining 19 studies were uncontrolled ( n = 15), 63,68,72,92,161,162,166–168,170,171,182–185 had croton oil, 186 tretinoin 91 or topical PUVA 183 as control treatment or used combination treatment with interferon‐α 169 …”