Successful Treatment of Brevibacterium Bacteremia Solely With Antimicrobial Therapy

Benson, Charles E.; Tatem, Luis

doi:10.7759/cureus.16004

Cited by 3 publications

(5 citation statements)

References 17 publications

(21 reference statements)

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“…Brevibacterium showed a preferable prognosis as most reported cases improved 48–72 h after the treatment [5] . Our patient presented with febrile illness and improved 2–3 days after starting appropriate management.…”

Section: Discussionmentioning

confidence: 97%

“…Brevibacterium is mainly found in habitat that has high salt concentration [4] . Also, it contributes to the aroma and color of the dairy product, body, human microbiota, and animals [5] , [6] . Furthermore, Brevibacterium was considered to be a contaminant, non-pathogenic bacterium.…”

Section: Discussionmentioning

confidence: 99%

“…Using vancomycin as a lock therapy was shown to be effective in combination with intravenous vancomycin. This assists in clearing uncomplicated bacteremia as well, as it may be used to keep the preciouses implanted foreign body in place [4] , [5] , [6] , [7] , [8] .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Brevibacterium Luteolum bacteremia: A case report and literature review

Munshi

Alsaedi

Baloush

et al. 2022

IDCases

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Brevibacterium Luteolum bacteremia: A case report and literature review

Munshi

Alsaedi

Baloush

et al. 2022

IDCases

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“…Given the lack of standardized treatment guidelines, management decisions were made based on available evidence and expert opinion [ 2 ]. Vancomycin has been used in immunocompromised patients, particularly those with cancer and HIV, for Brevibacterium bacteremia [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…The presence of Brevibacterium species in the cerebrospinal fluid (CSF) is exceedingly rare, with only a few reported cases in the literature [1]. The most common isolated species is Brevibacterium casei [2]. There are cases of osteomyelitis, endocarditis, brain abscess, and peritonitis [3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Unveiling Brevibacterium Species Isolated in the Cerebrospinal Fluid: A Report of a Rare Case

Nguyen,

Nand

2024

Cureus

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This case emphasizes the significance of recognizing and managing Brevibacterium species. Here, we present a unique case of Brevibacterium species isolated from the cerebrospinal fluid of a 60-year-old female with recently diagnosed human immunodeficiency virus (HIV) and small cell carcinoma of the lung. Management involved a two-week course of intravenous vancomycin. Brevibacterium species are infrequently encountered in clinical practice. Sharing this case report aims to enhance the limited understanding of Brevibacterium species infections and encourages discussion among healthcare professionals regarding its diagnosis and management.

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Discovery of <i>Brevibacterium</i> predominating in fecal samples from three children with persistent diarrhea negative for common pathogens

Quy,

Khoa,

Nga

et al. 2024

Vietnam J. Biotechnol.

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Acute diarrhea is a common disease in children under 5 years old and can develop into persistent diarrhea, greatly affecting the children's health. Although advanced techniques had been used to diagnose and detect common pathogens in hospitals, however, 40% of cases are negative for the pathogens. In this study, to investigate dominant bacteria in stool samples of three persistent-diarrheal children with unidentified pathogenic agents, the V3 and V68 regions of the 16S rRNA gene were amplified from fecal bacterial metagenomic DNA, separated on DGGE gel, and the dominant DNA bands were sequenced. As a result, the V3 and V68 regions of bacteria in persistent diarrheal children were less diverse and different from the corresponding DNA bands of the indicator strains. Sequence analysis and similarity comparison of six DNA bands of V3 regions and seven DNA bands of V68 regions showed that two V3 sequences (of 160 bp) derived from two samples were novel and did not match any genes from the non-redundant database, but they shared 93.75% similarity to each other. The four V3 sequences left derived from all three samples were the most similar (94.53-100%) with the corresponding genes of Brevibacterium. Six of the seven V68 sequences derived from dominant DNA bands of all three samples were the most similar (from 99.4% to 100%) to the corresponding genes of referent strains belonging to the genus Enterococcus. In sample D3, a sequence of the V68 region possessed 100% identity to the E. faecalis ATCC 19433 strain. This is the first study report that Brevibacterium was the dominant bacteria in the gastrointestinal microflora of children with persistent diarrhea although the bacterial genus has been reported to cause dangerous diseases in humans with immunodeficiency.

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Successful Treatment of Brevibacterium Bacteremia Solely With Antimicrobial Therapy

Abstract: Benson et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cited by 3 publications

References 17 publications

Brevibacterium Luteolum bacteremia: A case report and literature review

Brevibacterium Luteolum bacteremia: A case report and literature review

Unveiling Brevibacterium Species Isolated in the Cerebrospinal Fluid: A Report of a Rare Case

Discovery of <i>Brevibacterium</i> predominating in fecal samples from three children with persistent diarrhea negative for common pathogens

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