Objective: This study reports the effects of Korean medicine therapy for fatigue and anorexia after endoscopicretrograde cholangiopancreatography (ERCP) for common bile duct stone with cholangitis.Methods: A 76-year-old woman was admitted for fatigue and anorexia after ERCP and she was treated with <i>Hyansayangyi-tang-gami</i> as well as acupuncture, moxibustion, and cupping therapies. Symptoms were evaluated using a numericrating scale (NRS), and liver function was examined through laboratory test.Results: After 19 days of treatment, the patient’s fatigue improved from NRS 7 to NRS 4, and her anorexia score also improved, from NRS 9 to NRS 1~2. Liver function also increased.Conclusion: This study suggests that Korean medicine can be used for managing fatigue and anorexia following ERCP.