Successful Treatment of Granulomatous Reactions Secondary to Injection of Esthetic Implants

Lloret, Pedro; España, Agustín; Leache, A.; Bauzá, A.; Fernández-Galar, Marta; Idoate, Miguel A.; Plewig, Gerd; Weber, Lothar W.

doi:10.1097/00042728-200504000-00022

Cited by 22 publications

(8 citation statements)

References 11 publications

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“…daily or twice daily as tolerated. Isotretinoin, doxycycline, and topical imiquimod have also been used successfully to treat silicone granulomas (17,18). Granulomas that fail to resolve may require surgical removal.…”

Section: Side and Effects And Managing Complicationsmentioning

confidence: 99%

Liquid injectable silicone for soft tissue augmentation

Prather

Jones

2006

Dermatol Ther

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Liquid injectable silicone is a unique soft tissue augmenting agent that may be effectively utilized for the correction of specific cutaneous and subcutaneous atrophies. Although historical complications have occurred, resulting likely from the presence of adulterants and impurities, modern purified silicone products approved by the Food and Drug Administration for injection into the human body may be employed with minimal complications when strict protocol is followed. In this article the present authors review the history and controversy regarding silicone as well as describe the appropriate indications, patient selection, instrumentation, treatment protocol, and anticipated complications involved with the use of liquid injectable silicone for soft tissue augmentation. Although its use is controversial, the present authors maintain that liquid injectable silicone is an important and effective augmenting agent for the long-term correction of scars and facial contour defects such as HIV facial lipoatrophy. Furthermore, it is a treatment modality deserving of continued investigation.

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Section: Side and Effects And Managing Complicationsmentioning

confidence: 99%

Liquid injectable silicone for soft tissue augmentation

Prather

Jones

2006

Dermatol Ther

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“…Anecdotic reports have described improvement of the foreign body granulomas with colchicine, 53 laser therapy, 69 allopurinol, 70 cyclosporin, tacrolimus, ascomycin, 71 and isotretinoin. 72 …”

Section: Delayed-onset Complicationsmentioning

confidence: 99%

Foreign Body Granulomas

Molina-Ruiz¹,

Requena²

2015

Dermatologic Clinics

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“…Several granulomatous reactions have been reported after using medical and nonmedical-grade silicone. [16][17][18] Granulomata usually present late after injections, with tenderness, swelling, and at times suppuration. 19 Granulomata should be excised and must be confirmed by histological examination: silicone granulomata show intracellular and extracellular nonbirefringent vacuoles (►Fig.…”

Section: Granulomasmentioning

confidence: 99%

Management of Complications of Injectable Silicone

Hexsel¹,

Morais

2014

Facial plast Surg

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Soft tissue augmentation is a common procedure, and a wide variety of injectable fillers are used. Liquid injectable silicone (LIS) was the first highly popularized injectable filler. LIS is a permanent filler and can be used in the correction of facial furrows and wrinkles. Some complications are inherent to the procedure and can resolve spontaneously, such as redness, swelling, and immediate hypersensitivity reactions. Unintended reactions, such as granulomas, infections, vascular occlusion, can also follow the treatment with LIS and may appear several years after the injections. These can be difficult to manage, show little or no tendency to spontaneous resolutions, and rarely resolve completely. Injecting physicians must be aware of these potential complications caused by LIS because early medical care and treatment, including psychological support for these patients, can minimize the consequences for patients and physicians, and may also help obtaining better outcomes when treating complications.

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Successful Treatment of Granulomatous Reactions Secondary to Injection of Esthetic Implants

Cited by 22 publications

References 11 publications

Liquid injectable silicone for soft tissue augmentation

Liquid injectable silicone for soft tissue augmentation

Foreign Body Granulomas

Management of Complications of Injectable Silicone

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