Successful Treatment of Idiopathic Granulomatous Mastitis with Oral Prednisolone

Abstract

Idiopathic granulomatous mastitis was first described in 1972 by Kessler and Wolloch. It is a rare breast condition of unknown etiology. The challenge is to differentiate it most importantly from breast cancer and other causes of mastitis. In this report, we describe a successful response of idiopathic granulomatous mastitis to oral prednisolone (1mg/kg/day).The patient showed a significant decrease in the size of lesion with significant reduction in intensity of color and thickness, until almost total disappearance. Our experience suggests that steroid therapy may be recommended in all cases of idiopathic granulomatous mastitis as the first-line therapy.