Successful Treatment of Intracerebral Hydatid Cysts with Albendazole

Singounas, E. G.; Leventis, A. S.; Sakas, Damianos E.; Hadley, Donald M.; Lampadarios, D. A.; Karvounis, P. C.

doi:10.1097/00006123-199209000-00022

Cited by 21 publications

(26 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, we strongly disagree with their statement "in the majority of cases, cerebral echinococcosis is accompanied by lesions in lung or liver." Instead, hepatic or pulmonary locations were found in only 10-20% of patients with cerebral hydatid cysts [4,5]. 3.…”

mentioning

confidence: 99%

Infected or complicated hydatid case mimicking a primary brain tumor

Turgut

Turğut²

2002

Neurosurg Rev

View full text Add to dashboard Cite

mentioning

confidence: 99%

Infected or complicated hydatid case mimicking a primary brain tumor

Turgut

Turğut²

2002

Neurosurg Rev

View full text Add to dashboard Cite

“…However, pre- and postoperative albendazole may be considered in order to sterilize the cyst, decrease the chance of anaphylaxis, decrease the tension in the cyst wall (thus reducing the risk of spillage during surgery) and reduce the recurrence rate postoperatively [16, 17]. Although their efficacy was not sufficiently demonstrated, corticosteroids may be used to reduce the perifocal edema in selected cases.…”

Section: Discussionmentioning

confidence: 99%

The Clinical, Radiological and Surgical Aspects of Cerebral Hydatid Cysts in Children

Tüzün¹,

Kadıoğlu²,

İzci

et al. 2004

Pediatr Neurosurg

View full text Add to dashboard Cite

A series of 13 pediatric patients underwent surgery for cerebral hydatid cysts at the Department of Pediatric Neurosurgery between 1993 and 2003. Headache and motor weakness were the main initial signs of these patients. A round cystic lesion was the characteristic appearance on computed tomography of each patient. Different cyst locations such as the liver, kidney or spleen were detected in 5 patients. Surgery using Dowling’s technique was performed in all patients as the main treatment. Intraoperative rupture and cyst recurrence were observed in only 1 patient. Subdural effusion, intraparenchymal air and hemorrhage were the main complications observed after surgery. None of the patients died after surgery. Because of its efficacy combined with excellent results, surgery is currently the method of choice in the treatment of cerebral hydatid cyst in children.

show abstract

“…The chemotherapy of human hydatid disease could be of great importance in patients with inoperable cysts or multiple cysts and in those who are unfit for surgery or may be suffering from recurrent disease [10,11,32,34,60,70,73,87,92,96,97,102,103]. Antihelminthic agents for the medical treatment of hydatid disease in both types of echinococcosis in humans as an adjunct to surgical intervention are mebendazole and albendazole [11,32,34,60,65,87,92,97].…”

Section: Intracranial Hydatid Cystsmentioning

confidence: 99%

“…Antihelminthic agents for the medical treatment of hydatid disease in both types of echinococcosis in humans as an adjunct to surgical intervention are mebendazole and albendazole [11,32,34,60,65,87,92,97]. In 1988, Todorov et al [92] reported a patient with multiple hydatid cysts who was successfully treated with albendazole.…”

Section: Intracranial Hydatid Cystsmentioning

confidence: 99%

“…In 1988, Todorov et al [92] reported a patient with multiple hydatid cysts who was successfully treated with albendazole. Consideration of the effects of both these drugs in the management of CNS hydatidosis reveals that so far their use has been successful in recurrent cases insofar as they have led to regression or arrest of growth of echinococcal lesions, probably by interfering with uptake of glycogen by the cestodes [33,69,80,87]. I think that further randomized studies are now needed so that information allowing a correct decision on the role of these chemotherapeutic agents in CNS hydatidosis can be won.…”

Section: Intracranial Hydatid Cystsmentioning

confidence: 99%

See 1 more Smart Citation

Hydatidosis of central nervous system and its coverings in the pediatric and adolescent age groups in Turkey during the last century: a critical review of 137 cases

Turğut

2002

Child's Nervous System

View full text Add to dashboard Cite

Despite the inherent limitations, this type of study indicates that the incidence of hydatidosis has not decreased in Turkey in recent years. The clinical findings were mostly atypical, and it was interesting that 4 patients were described as having cerebrovascular occlusive disease and 3 as having symptoms of movement disorders. Computed tomography and/or MRI techniques were extremely useful, both in reaching the correct diagnosis and for proper surgical management of hydatid disease, because of the absence of a pathognomonic clinical picture of this disease. The treatment of choice for hydatid disease of the CNS and its coverings was complete intact removal of the cyst. In contrast to that in intracranial hydatid cysts, however, surgical intervention was palliative, not curative, in almost all cases of intraspinal hydatidosis. According to this critical review of the literature, CNS hydatidosis is therefore still a life-threatening condition, in spite of all the advances in imaging techniques and therapeutic methods. The most important factors in prognosis are the localization of the focus of infection, rupture and of the cyst and dissemination of its content, and treatment modality. At present, surgical intervention preceded by careful neuroradiological evaluation remains the best surgical therapy, and this plus adjuvant chemotherapy is advocated in some cases as the gold standard for therapy.

show abstract

Successful Treatment of Intracerebral Hydatid Cysts with Albendazole

Cited by 21 publications

References 6 publications

Infected or complicated hydatid case mimicking a primary brain tumor

Infected or complicated hydatid case mimicking a primary brain tumor

The Clinical, Radiological and Surgical Aspects of Cerebral Hydatid Cysts in Children

Hydatidosis of central nervous system and its coverings in the pediatric and adolescent age groups in Turkey during the last century: a critical review of 137 cases

Contact Info

Product

Resources

About