Successful treatment of Kasabach–Merritt syndrome with transarterial embolization and corticosteroids

Zhou, Shaoyi; Li, Haibo; Mao, Yue-ming; Liu, Peiying; Zhang, Jing

doi:10.1016/j.jpedsurg.2012.12.049

Cited by 20 publications

(12 citation statements)

References 17 publications

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“…Antifibrinolytic agents (e.g., aminocaproic acid or tranexamic acid) have been used with mixed responses, as have antiplatelet agents such as aspirin or dipyridamole. Other medical options that have a role in isolated cases include compression when lymphedema is present and embolization therapy or resection when an isolated lesion or feeding vessel is documented . Radiation therapy is also reported to be effective for KHE in refractory cases.…”

Section: Kaposiform Hemangioendothelioma With Kasabach–merritt Phenommentioning

confidence: 99%

Vascular anomaly cases for the pediatric hematologist oncologists—An interdisciplinary review

Adams

Brandão

Peterman

et al. 2017

Pediatric Blood & Cancer

106

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Vascular anomalies (VAs) are classified as tumors or malformations depending on their clinical characteristics, pathological diagnosis, and genomic information. Diagnosis can be challenging because of the heterogeneity of clinical presentation; thus, the best diagnosis and care are provided by an interdisciplinary team of specialists. Over the past 10 years, an increasing number of pediatric hematologist/oncologists are caring for patients with VAs secondary to new medical therapy options and clinical trials. This paper focuses on complicated VA issues often seen by the pediatric hematologist/oncologist. The paper reviews clinical pearls on diagnosis, histology, radiology, and treatment options.

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Section: Kaposiform Hemangioendothelioma With Kasabach–merritt Phenommentioning

confidence: 99%

Vascular anomaly cases for the pediatric hematologist oncologists—An interdisciplinary review

Adams

Brandão

Peterman

et al. 2017

Pediatric Blood & Cancer

106

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“…In large tumors, TAE can be a useful bridge before surgery is attempted or until the systemic treatment becomes effective [43,101,102]. There are also multiple case reports of successful treated KMS with endovascular approaches [103][104][105][106]. As mentioned in Table 1, KMS secondary to liver hemangiomas [107] and Merkel cell cancer involving the face [108] has been successfully treated with TAE.…”

Section: Others Embolizationmentioning

confidence: 99%

Clinical Review: Management of Adult Kasabach-Merritt Syndrome Associated with Hemangiomas

Master¹,

Kallam²,

Eo³

et al. 2017

J Blood Disord Transfus

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Kasabach-Merritt syndrome (KMS) consists of a clinical trial of capillary hemangioma, thrombocytopenia and disseminated intravascular coagulation. KMS occurs most commonly in the pediatric population, and its occurrence in adults is rare. Specific guidelines or randomized clinical trials guiding clinical management of KMS in adult patients are lacking. This manuscript provides a comprehensive review of KMS and discusses recent advances in the medical management of KMS. We also propose a systematic therapeutic approach which would serve as a guide in the management of adult patients with KMS caused by hemangiomas.

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“…Low dose radiotherapy, angio-embolisation, chemo-embolisation, and intralesional bleomycin/ ethanol has also been described recently in literature. [9][10][11] Treatment with propranolol, steroids, and intralesional bleomycin did not work in the index case.…”

Section: Discussionmentioning

confidence: 95%

Massive Congenital Vascular Tumor of Lower Limb: Kaposiform Hemangioendothelioma

Sarin

Kumar

2018

J Neonat Surg

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACTWe report a neonate with congenital Kaposiform hemangioendothelioma of left thigh and diagnostic dilemmas encountered in the management. The lesion was dealt with en-bloc resection in early infancy which was proven curative. Currently patient is doing well on follow-up.

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Successful treatment of Kasabach–Merritt syndrome with transarterial embolization and corticosteroids

Cited by 20 publications

References 17 publications

Vascular anomaly cases for the pediatric hematologist oncologists—An interdisciplinary review

Vascular anomaly cases for the pediatric hematologist oncologists—An interdisciplinary review

Clinical Review: Management of Adult Kasabach-Merritt Syndrome Associated with Hemangiomas

Massive Congenital Vascular Tumor of Lower Limb: Kaposiform Hemangioendothelioma

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