Abstract:Malakoplakia is a rare granulomatous infectious process that affects patients with primary or secondary immunodeficiency. 1 Abnormal macrophage bactericidal activity leads to mass-forming aggregates of histiocytes containing bacteria and pathognomonic basophilic inclusions called Michaelis-Gutmann bodies (MGB). [2][3][4][5][6] The latter are concentrically laminated, round to ovoid concretions of calcium and iron that form within phagolysosomes with bacteria. Histiocytes containing MGB are called "von Hanseman… Show more
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