Successful Treatment of Malignant Hyperthermia

Leigh, M. Digby; Lewis, George B.; Scott, Edward B.; Herbert, Wayne I.

doi:10.1213/00000539-197101000-00007

Search citation statements

Order By: Relevance

Paper Sections

Select...

Treatment1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1975

2019

Publication Types

Select...

Article4

Book1

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 5 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An increase in temperature is subsequently distinguished early and the circulation of cold water can be started promptly, which could be kept up by flowing water sleeping cushion on the surgical table. Furthermore, cold lactated Ringer's solution administered intravenously, and ice packs are set around the patient's neck, in the axillae, and in the groins …”

Section: Treatmentmentioning

confidence: 99%

Overactivation of the sodium–calcium exchanger and transient receptor potential in anesthesia‐induced malignant hyperthermia

et al. 2019

View full text Add to dashboard Cite

Malignant hyperthermia is a pharmacogenetic disorder, which is an uncommon but frequently fatal intricacy of inhalation anesthesia in man. It causes a quick rise in body temperature to highly irreversible levels, which causes death in around three of four cases. The trigger anesthetics cause an anomalous, continued ascent in myoplasmic calcium levels. Possible mechanisms by which continuous release of sodium, calcium from skeletal muscle plasma membrane and sarcoplasmic reticulum stores respectively can produce the profound hyperthermia are discussed.anesthesia, calcium, GABA, malignant hyperthermia, sarcoplasmic reticulum

show abstract

Section: Treatmentmentioning

confidence: 99%